RTI uses cookies to offer you the best experience online. By clicking “accept” on this website, you opt in and you agree to the use of cookies. If you would like to know more about how RTI uses cookies and how to manage them please view our Privacy Policy here. You can “opt out” or change your mind by visiting: http://optout.aboutads.info/. Click “accept” to agree.
Antimutagenic agents from natural products of terrestrial and marine origin
Wall, M., & Wani, M. (1993). Antimutagenic agents from natural products of terrestrial and marine origin. In G. Bronzetti, H. Hayatsu, S. Flora, & D. M. Shankel (Eds.), Antimutagenesis and Anticarcinogenesis Mechanisms III (Vol. 61, pp. 87-97). Springer Nature. https://link.springer.com/chapter/10.1007/978-1-4615-2984-2_7
Both chemists and biologists have been intrigued for many years by the role of secondary metabolites in plants of terrestrial and marine origins. Of equal interest is whether such compounds have antitumor, antiviral, or antimutagenic properties. For example, the highly active antitumor agents, camptothecin and taxol, have been isolated from the bark and wood of trees (13,21), and another active agent, bryostatin I, from a marine animal (11). Dudley Williams has proposed that “secondary metabolites are a measure of the fitness of the organism to survive by repelling or entrapping other organisms” (23). Mitscher has stated that “as some constituents of higher plants are mutagens, it seems reasonable that substances capable of antimutagenicity also be produced by such plants” (10).
RTI shares its evidence-based research - through peer-reviewed publications and media - to ensure that it is accessible for others to build on, in line with our mission and scientific standards.