• Journal Article

Airborne copper exposure in school environments associated with poorer motor performance and altered basal ganglia

Citation

Pujol, J., Fenoll, R., Macià, D., Martínez-Vilavella, G., Alvarez-Pedrerol, M., Rivas, I., ... Sunyer, J. (2016). Airborne copper exposure in school environments associated with poorer motor performance and altered basal ganglia. Brain and Behavior, 6(6), e00467. DOI: 10.1002/brb3.467

Abstract

Higher copper exposure was associated with poorer motor performance and altered structure of the basal ganglia. Specifically, the architecture of the caudate nucleus region was less complete in terms of both tissue composition and neural track water diffusion. Functional MRI consistently showed a reciprocal connectivity reduction between the caudate nucleus and the frontal cortex. The results establish an association between environmental copper exposure in children and alterations of basal ganglia structure and function.