10,11-methylenedioxy camptothecins
Wani, M., Nicholas, A., & Wall, M. (1992). 10,11-methylenedioxy camptothecins. (U.S. Patent No. 5122606). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=5122606
Abstract
The invention relates to a method of producing 20(S)-camptothecin, 20(R)-camptothecin and analogs thereof. The method involves the resolution of an mixture of enantiomers of an intermediate lactone.
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