10,11-methylenedioxy camptothecins

Wani, M., Nicholas, A., & Wall, M. (1992). IPC No. U.S. 10,11-methylenedioxy camptothecins. (U.S. Patent No. 5122606). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=5122606

Abstract

The invention relates to a method of producing20(S)-camptothecin, 20(R)-camptothecin and analogs thereof. Themethod involves the resolution of an mixture of enantiomers of anintermediate lactone.

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