10,11-methylenedioxy camptothecins
The invention relates to a method of producing20(S)-camptothecin, 20(R)-camptothecin and analogs thereof. Themethod involves the resolution of an mixture of enantiomers of anintermediate lactone.
Citation
Wani, M., Nicholas, A., & Wall, M. (1992). IPC No. U.S. 10,11-methylenedioxy camptothecins. (Patent No. 5122606).