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Stephanie R. Earnshaw

Research Management Scientist, RTI-HS

Stephanie Earnshaw, PhD, applies mathematical modeling, optimization, and decision analysis techniques to industry-related issues and health care problems. She has also extensive experience in survey management. Her areas of specialization include systems optimization and solving resource allocation problems. She has developed innovative mathematical models to determine pricing strategy, budget impact, and cost-effectiveness of new products. Dr. Earnshaw has developed a variety of mathematical models, including Markov models, Monte Carlo simulation models, and other state transition models, to analyse the impact of new medical interventions on disease progression. Dr. Earnshaw also has extensive programming experience and has led programmers in developing user interfaces for health surveys and for several pharmacoeconomic models. Dr. Earnshaw is a member of the Institute for Operations Research and the Management Sciences. She has presented her work at professional conferences and has published in several peer-reviewed journals.


PhD, Industrial Engineering (Operations Research and Management), North Carolina State University; MS, Industrial Engineering (Operations Research), North Carolina State University; BS, Mathematical Science (Operations Research), University of North Carolina at Chapel Hill.

Latest Publications

Barnes, R., Earnshaw, S., Herbrecht, R., Morrissey, O., Slavin, M., Bow, E., McDade, C., et al. (2015). Economic Comparison of an Empirical Versus Diagnostic-Driven Strategy for Treating Invasive Fungal Disease in Immunocompromised Patients. Clinical Therapeutics, 37 (6):1317-1328.
Earnshaw, S.R., Graham, C.N., McDade, C.L., Spears, J.B., & Kessler, C.M. (2015). Factor VIII alloantibody inhibitors: Cost analysis of immune tolerance induction vs. prophylaxis and on-demand with bypass treatment. Haemophilia, 21 (3):310-319.
Ward, M.A., Fang, G., Richards, K.L., Walko, C.M., Earnshaw, S.R., Happe, L.E., et al. (2015). Comparative evaluation of patients newly initiating first-generation versus second-generation tyrosine kinase inhibitors for chronic myeloid leukemia and medication adherence, health services utilization, and healthcare costs. Current Medical Research and Opinion, 31 (2):289-297.
Kamat, S., Blanchette, C., Wilson, M., Tangirala, M., Earnshaw, S.R., Offord, S., et al. (2014). Healthcare Cost Savings Associated With Aripiprazole Once-Monthly (AOM) Treatment Among Schizophrenia Patients With Psychiatric Hospitalizations Prior to AOM Treatment Initiation. Presented at ISPOR 19th Annual International Meeting, June 2014.
Hogue, S., Brogan, A.P., Earnshaw, S., Khan, S., & Nelsen, S.H. (2014). Academy of Managed Care Pharmacy Dossiers: Use in Health Care Decision Making. Presented at ISPOR 19th Annual International Meeting, May 2014.
View all publications by Stephanie R. Earnshaw (92)


  • Health Economics
  • Pharmacoeconomics
  • Operations Research