RTI Press Method Report
Use of secondary population-based databases to evaluate the safety of medications
Tennis, P.S., Andrews, E.B., Lanza, L.L., & Johannes, C.B. (September 2008).
Large electronic databases, such as electronic medical records, are powerful tools for evaluating drug safety, i.e. quantifying the frequency of possible adverse health effects of a specific drug, according to a new synthesis by researchers at RTI International.
The paper summarizes the data resources available for detection and evaluation of safety signals for possible adverse events related to drugs, and describes the resources and methods used in drug safety research. According to the researchers, the most relevant and available data resources primarily include anonymized electronic health care claims and electronic medical records and can be used to identify new safety issues and to evaluate known or suspected problems.
Full Document: RTI Press - Method Report 
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Permanent Link: doi:10.3768/rtipress.2008.mr.0007.0809
Full Citation: Tennis, P.S., Andrews, E.B., Lanza, L.L., & Johannes, C.B. (September 2008). Use of secondary population-based databases to evaluate the safety of medications. RTI Press Publication No. MR-0007-0809.
Abstract
Large electronic databases, such as electronic medical records, are powerful tools for evaluating drug safety, i.e. quantifying the frequency of possible adverse health effects of a specific drug, according to a new synthesis by researchers at RTI International.The paper summarizes the data resources available for detection and evaluation of safety signals for possible adverse events related to drugs, and describes the resources and methods used in drug safety research. According to the researchers, the most relevant and available data resources primarily include anonymized electronic health care claims and electronic medical records and can be used to identify new safety issues and to evaluate known or suspected problems.
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