Chunyang Jin

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FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2–induced resistance

Reversal of Ethanol-induced Intoxication by a Novel Modulator of Gβγ Protein Potentiation of the Glycine Receptor

Indole-containing amidinohydrazones as nonpeptide, dual RXFP3/4 agonists: Synthesis, structure–activity relationship, and molecular modeling studies

Synthesis of N6-[endo-2'-(endo-5'-Hydroxy)norbornyl]-8-(N-methylisopropylamino)-9-methyladenine (WRC-0571): A potent and selective adenosine A1 receptor antagonist

Chemical synthesis and structural elucidation of a new serotonin metabolite: (4R)-2-[(5'-hydroxy-1'H-indol-3'-yl)methyl]thiazolidine-4-carboxylic acid

Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter

New Study Suggests a Potential Novel Drug Target for Alcoholism

Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator-a hybrid structure of 17beta-estradiol and vitamin e in hippocampal neurons

Design, synthesis, and structure-activity relationship studies of (4-alkoxyphenyl)glycinamides and bioisosteric 1,3,4-oxadiazoles as GPR88 agonists

Design, synthesis, and structure–activity relationship studies of novel GPR88 agonists (4-substituted-phenyl)acetamides based on the reversed amide scaffold

Synthesis and antihormonal properties of novel 11ß-benzoxazole-substituted steroids

Targeting the relaxin-3/RXFP3 system: A patent review for the last two decades

Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase

Improvement of the metabolic stability of GPR88 agonist RTI-13951-33: Design, synthesis, and biological evaluation

Synthesis of carnosine-d7 and anserine-d4 for use as internal standards in liquid chromatography-mass spectrometry

Synthesis, Pharmacological Characterization, and Structure-Activity Relationship Studies of Small Molecular Agonists for the Orphan GPR88 Receptor

Synthesis and monoamine transporter binding properties of 2ß-[3'-(substituted benzyl)isoxazol-5-yl]- and 2ß-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3ß-(substituted phenyl)tropanes

1-substituted 4-arylpiperazine as kappa opioid receptor antagonists

Effect of substitution on the aniline moiety of the GPR88 agonist 2-PCCA: Synthesis, structure-activity relationships, and molecular modeling studies