Ann Decker

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Indole-containing amidinohydrazones as nonpeptide, dual RXFP3/4 agonists: Synthesis, structure–activity relationship, and molecular modeling studies

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3-and 4-methyl substituents

Fluoroalkoxylated C-3 and C-9 (S)-12-bromostepholidine analogues with D1R antagonist activity

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor

The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7

2018 College on Problems of Drug Dependence Annual Meeting

Discovery of 1,3-disubstituted pyrazole peripheral cannabinoid receptor partial agonists

Diarylureas containing 5-membered heterocycles as cb1 receptor allosteric modulators: Design, synthesis, and pharmacological evaluation

Development of serotonin transporter reuptake inhibition assays using JAR cells

Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor

Development of 3-(4-chlorophenyl)-1-(phenethyl)urea analogues as allosteric modulators of the cannabinoid type-1 receptor: RTICBM-189 is brain penetrant and attenuates reinstatement of cocaine-seeking behavior

Synthesis and pharmacological evaluation of 1-phenyl-3-thiophenylurea derivatives as cannabinoid type-1 receptor allosteric modulators

Design, synthesis, and structure-activity relationship studies of (4-alkoxyphenyl)glycinamides and bioisosteric 1,3,4-oxadiazoles as GPR88 agonists

Design, synthesis, and structure–activity relationship studies of novel GPR88 agonists (4-substituted-phenyl)acetamides based on the reversed amide scaffold

Interaction of psychoactive tryptamines with biogenic amine transporters and serotonin receptor subtypes

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction

Alpha-ethyltryptamines as dual dopamine-serotonin releasers

Improvement of the metabolic stability of GPR88 agonist RTI-13951-33: Design, synthesis, and biological evaluation

Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids