Download image:

Doris J. Rouse

Vice President, Global Health Technologies

Doris Rouse, PhD, manages the coordination of diverse disciplines to address major global health needs. Currently, she is the project director for two Gates Foundation grants: Venture Investment Technical Assistance to develop new products for global health, and Maternal and Neonatal Directed Assessment of Technology (MANDATE) to identify and advance opportunities for improving maternal and neonatal health in low resource settings. Dr. Rouse is the principal investigator for a program funded by the National Institutes of Health to commercialize new treatments for tuberculosis. She has extensive experience in forming public and private consortia, such as the Global Alliance for TB Drug Development. Dr. Rouse serves on the Global Health Advisory Committee for the University of North Carolina School of Public Health. In her tenure as director of the Center for Technology Applications at RTI, she managed technology assessment, outlicensing, and technology sourcing projects for numerous government and corporate clients.


PhD, Physiology and Pharmacology, Duke University; BA, Chemistry, Duke University.

Latest Publications

Winter, H., Egizi, E., Murray, S., Erondu, N., Ginsberg, A., Rouse, D.J., Severynse-Stevens, D., & Pauli, E. (2015). Evaluation of the Pharmacokinetic Interaction between Repeated Doses of Rifapentine or Rifampicin and a Single Dose of Bedaquiline in Healthy Adult Subjects. Antimicrobial Agents and Chemotherapy, 59 (2):1219-1224.
McClure, E.M., Jones, B., Rouse, D.J., Griffin, J.B., Kamath-Rayne, B.D., Downs, A., et al. (2014). Tranexamic Acid to Reduce Postpartum Hemorrhage: A MANDATE Systematic Review and Analyses of Impact on Maternal Mortality. American Journal of Perinatology, Advance Online Publication .
Winter, H., Egizi, E., Erondu, N., Ginsberg, A., Rouse, D.J., Severynse-Stevens, D., Pauli, E., et al. (2013). Evaluation of pharmacokinetic interaction between PA-824 and midazolam in healthy adult subjects. Antimicrobial Agents and Chemotherapy, 57 (8):3699-3703.
McClure, E.M., Rouse, D.J., MacGuire, E.R., Jones, B., Griffin, J.B., Jobe, A.H., et al. (2013). The MANDATE model for evaluating interventions to reduce postpartum hemorrhage. International Journal of Gynecology & Obstetrics, 121 (1):5-9.
Diacon, A.H., Dawson, R., Hanekom, M., Narunsky, K., Maritz, S.J., Venter, A., Donald, P.R., van Niekerk, C., Whitney, K., Rouse, D.J., et al. (2010). Early Bactericidal Activity and Pharmacokinetics of PA-824 in Smear-Positive Tuberculosis Patients. Antimicrobial Agents and Chemotherapy, 54 (8):3402-3407.
View all publications by Doris J. Rouse (21)