Ligands for .alpha.-7 nicotinic acetylcholine receptors based on methyllcaconitine
Carroll, F., Navarro, H., Abraham, P., & Zhong, D. (2002). Ligands for .alpha.-7 nicotinic acetylcholine receptors based on methyllcaconitine. (U.S. Patent No. 6416735). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=6416735
Abstract
Ligands for nAChRs are provided based on various derivatives of methyllycaconitine (MLA) such as radiolabeled MLA, and MLA containing a fluorimetric marker group and their use in imaging for detection of Alzheimer's and other CNS diseases, and combinatorial assays for detection of compounds having affinity for nAChRs, as well as injectable compositions containing the same and kits for performing the imaging studies.
To contact an RTI author, request a report, or for additional information about publications by our experts, send us your request.