Hexahydroindenopyridine compounds having antispermatogenic activity
Cook, C., Lee, Y., Wani, M., Fail, P., & Jump, J. (1994). Hexahydroindenopyridine compounds having antispermatogenic activity. (U.S. Patent No. 5319084). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=5319084
Abstract
Hexahydroindenopyridine compounds having the following formula and relative stereochemistry ##STR1## where R.sup.1 is C.sub.1-6 alkyl, R.sup.2 is hydrogen or C.sub.1-6 alkyl and R.sup.3 is carboxyl or a group which is metabolized to a carboxyl group under mammalian physiological conditions exhibit potent antispermatogenic activity and are useful in a method of inhibiting spermatogenesis in mammals.
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