Improving the identification of out-of-hospital sudden cardiac deaths in a general practice research database
Varas-Lorenzo, C., Arana, A., Johannes, C., McQuay, L., Rothman, K., & Fife, D. (2016). Improving the identification of out-of-hospital sudden cardiac deaths in a general practice research database. Drugs - Real World Outcomes, 3(3), 353-358. Advance online publication. https://doi.org/10.1007/s40801-016-0086-1
Our algorithm to identify end-of-life care at home in the CPRD performed well, with only one false negative. The exclusion of misclassified cases of SCD reduced the magnitude of the odds ratios for SCD associated with domperidone and metoclopramide exposure by controlling protopathic bias.
