• Journal Article

Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter

Citation

Thiruvazhi, M., Abraham, P., Kuhar, M. J., & Carroll, F. (1997). Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter. Chemical Communications, (6), 555-556.

Abstract

The syntheses of all four isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester are described; the 2 beta,3 beta-isomer shows high affinity for the cocaine binding site on the dopamine transporter