Short-term outcomes of infants enrolled in randomized clinical trials vs those eligible but not enrolled
Foglia, E. E., Nolen, T., DeMauro, S. B., Das, A., Bell, E. F., Stoll, B. J., & Schmidt, B. (2015). Short-term outcomes of infants enrolled in randomized clinical trials vs those eligible but not enrolled. JAMA: Journal of the American Medical Association, 313(23), 2377-2379. DOI: 10.1001/jama.2015.5734
It is unknown whether participation in a neonatal randomized clinical trial (RCT) is independently associated with differences in outcomes. Our objective was to compare in-hospital outcomes between extremely premature infants enrolled in RCTs and those who were eligible but not enrolled in RCTs conducted by the National Institute of Child Health and Human Development Neonatal Research Network (NRN).