QPR 2: Second Quarterly Progress Report for NIH Project N01-DC-2-1002 (July 1 through September 30, 2002) -- Speech Processors for Auditory Prostheses
The main objective of this project is to design, develop, and evaluate speech processors for implantable auditory prostheses. Ideally, such processors will represent the information content of speech in a way that can be perceived and utilized by implant patients. An additional objective is to record responses of the auditory nerve to a variety of electrical stimuli in studies with patients. Results from such recordings can provide important information on the physiological function of the nerve on an electrode-by-electrode basis, and can be used to evaluate the ability of speech processing strategies to produce desired spatial or temporal patterns of neural activity. Work and activities in this quarter included: • The beginning of studies with local bilaterally implanted subject ME-16 • Continuing studies with local bilaterally implanted subject ME-12 • The arrival of Dr. Xiaoan Sun, who will provide engineering support for the project • Presentation by Blake Wilson of a keynote lecture to the Seventh International Cochlear Implant Conference in Manchester, UK • Studies with a new bilaterally implanted subject, ME-17 • Preparation for studies with percutaneous subjects to begin evaluations of a new type of processing strategy, including nonlinearities designed to mimic functions of the normal ear • Completion of arrangements with Duke University Medical Center and Cochlear Corporation for studies involving percutaneous access to experimental perimodiolar electrode arrays in at least four subjects. In this report, we describe recent work with bilateral subjects ME-12 and ME-16. The results from other work done this quarter will be included in subsequent reports.