• Patent

Method for making cocaine receptor binding ligands and intermediates therefor

Citation

Carroll, F. (2000). IPC No. U.S.Method for making cocaine receptor binding ligands and intermediates therefor (Patent No. 6123917.)

Abstract

An improved method for preparation of cocaine receptor binding ligands is provided. The method calls for the preparation of the silylaryl intermediate prepared from phenyl trimethylsilane and a anhydroecgonine methyl ester appropriately substituted. The intermediate is prepared in high purity and can be directly converted to the binding ligand by iodine substitution.