• Article

Autism symptoms across adulthood in men with Fragile X syndrome A cross-sectional analysis

A cross-sectional analysis was used to examine age-related differences in ASD symptoms and corresponding differences in disruptive behavior and social skills in 281 adult men with fragile X syndrome. Four age groups were created: 18-21, 22-29, 30-39, and 40-49 years. The 18-21 year-old group was reported to have more impairments in verbal communication than the 22-29 year-old group and more restricted and repetitive behaviors than the 40-49 year-old group. There was not an age-group difference in the percentage of men who met criteria for an ASD diagnosis based on respondent-reported, current symptoms. There was a trend for an age-related difference in disruptive behavior. Findings add to understanding of the developmental trajectory of ASD symptoms in adulthood.


Hartley, SL., Wheeler, A., Mailick, MR., Raspa, M., Mihaila, I., Bishop, E., & Bailey, D. (2015). Autism symptoms across adulthood in men with Fragile X syndrome: A cross-sectional analysis. Journal of Autism and Developmental Disorders, 45(11), 3668-3679. https://doi.org/10.1007/s10803-015-2513-7, https://doi.org/10.1007/s10803-015-2513-7

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