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17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and their progestational use

Cook, C., Tallent, C., Reel, JR., & Wani, M. (1989). IPC No. U.S. 17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and their progestational use. (U.S. Patent No. 4861763). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=4861763

Abstract

Steroids of the formula: ##STR1## which are characterized by a17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, orethynylmethyl substituent and a 17.beta.-hydroxy/esterified hydroxysubstitutent. The steroids of this invention have glucocorticoid,anti-glucocorticoid, progrestational, or anti-progestationalactivity, depending on the particular structure.

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