17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and their progestational use
Citation
Cook, C., Tallent, C., Reel, J. R., & Wani, M. (1989). IPC No. U.S.17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and their progestational use (Patent No. 4861763.)
Abstract
Steroids of the formula: ##STR1## which are characterized by a 17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or ethynylmethyl substituent and a 17.beta.-hydroxy/esterified hydroxy substitutent. The steroids of this invention have glucocorticoid, anti-glucocorticoid, progrestational, or anti-progestational activity, depending on the particular structure.