Publications Related to "F. Ivy Carroll"

Article

Synthesis and characterization of the selective, reversible pkcβ inhibitor (9 s)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9 h,18 h-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 h)-dione, ruboxistaurin (ly33

The demonstrated role of PKCβ in mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and activity, has promoted the research use of the selective, reversible PKCβ inhibitor (9 S)-...

Article

Synthesis of enantiopure PZM21

PZM21 (1) was recently reported as a biased agonist of the mu-opioid receptor (MOR) with improved antinociceptive effects and reduced side effects compared with traditional opioid-based analgesics. The original synthesis of PZM21 with the desired...

Article

Caged Naloxone

The photolabile analogue of the broad-spectrum opioid antagonist naloxone, 3-O-(4,5-dimethoxy-2-nitrophenyl)carboxymethyl naloxone (also referred to as "caged naloxone", 3-O-(alpha-carboxy-6-nitroveratryl)naloxone, CNV-NLX), has been found to be...

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