Publications Related to "F. Ivy Carroll"


Synthesis and characterization of the selective, reversible pkcβ inhibitor (9 s)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9 h,18 h-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 h)-dione, ruboxistaurin (ly33

The demonstrated role of PKCβ in mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and activity, has promoted the research use of the selective, reversible PKCβ inhibitor (9 S)-...


Synthesis of enantiopure PZM21

PZM21 (1) was recently reported as a biased agonist of the mu-opioid receptor (MOR) with improved antinociceptive effects and reduced side effects compared with traditional opioid-based analgesics. The original synthesis of PZM21 with the desired...