Publications Related to "Allen W. Mangel"


Clinical trial

Background Dextofisopam modulates stimulated activity in animal models of stress, altered bowel motility, and visceral hypersensitivity. Aim To evaluate the effects of dextofisopam in men and women with diarrhoea-predominant or...


Primary endpoints for irritable bowel syndrome trials

The choice of primary endpoint for a clinical trial is one of the most important determinants of the ability of a clinical trial to demonstrate efficacy of therapeutic agents. Although there are still no clear, universally accepted guidelines on...