Published Research Abstract


Title: 

7-substituted camptothecin and camptothecin analogs and methods for producing the same

Patent No.: 7067666
Type: Patent
Date: 2006
Authors: Wani, M.C., Manikumar, G., Wall, M.A., Wall, M.E.
Abstract:Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.
Online Resources: Patent Details (US PTO)
Full Citation: Wani, M.C., Manikumar, G., Wall, M.A., & Wall, M.E. (2006). 7-substituted camptothecin and camptothecin analogs and methods for producing the same. U.S. Patent No. 7,067,666. Washington, D.C.: U.S. Patent and Trademark Office