| Title: | Camptothecin analogs having an E-ring ketone |
| Patent No.: | 7071204 |
| Type: | Patent |
| Date: | 2006 |
| Authors: | Wall, M.A., Wani, M.C., Manikumar, G., Wall, M.E. |
| Abstract: | Camptothecin analogs having an E-ring ketone are effective anti
tumor compounds. These compounds inhibit the enzyme topoisomerase I
and may alkylate DNA of the associated topoisomerase I DNA
cleavable complex. |
| Online Resources: | Patent Details (US PTO) |
| Full Citation: | Wall, M.A., Wani, M.C., Manikumar, G., & Wall, M.E. (2006). Camptothecin analogs having an E-ring ketone. U.S. Patent No. 7,071,204. Washington, D.C.: U.S. Patent and Trademark Office |
