Auditory Prosthesis Research Reports
Quarterly Progress Reports to the National Institutes of Health
Reports from Contract N01-DC-2-1002 (2002-2005), Contract N01-DC-8-2105 (1998-2002), Contract N01-DC-5-2103 (1995-1998) , Contract N01-DC-2-2401 (1992-1995), Contract N01-DC-9-2401 (1989-1992), Contract N01-NS-5-2396 (1985-1989), and Contract N01-NS-2356 (1983-1985) can be read from this site.
These reports are available in PDF format through the Neural Prosthesis Development Web site of the National Institutes of Health (NIH).
Contract N01-DC-2-1002 (2002-2006)
| No. | Title | Date | Link |
| QPR FINAL | Major areas of research under this contract and suggested future directions | Apr 1, 2002 - Mar 31, 2006 | PDF (100 kB) |
| QPR 15 | Results from the Nucleus percutaneous studies | Oct 1 - Dec 31, 2005 | PDF (251 kB) |
| QPR 14 | Further progress in the Nucleus percutaneous studies | Jul 1 - Sep 30, 2005 | PDF (47 kB) |
| QPR 13 | Progress in the Nucleus percutaneous studies | Apr 1 - Jun 30, 2005 | PDF (162 kB) |
| QPR 12 | Initial studies with a recipient of the PULSAR implant system | Jan 1 - Mar 31, 2005 | PDF (44 kB) |
| QPR 11 | Laboratory interface for the new Med-El PULSARci100 implant | Oct 1 - Dec 31, 2004 | PDF (428 kB) |
| QPR 10 | Pitch ranking of electrodes for 22 subjects with bilateral implants and melody recognition tests for cochlear implant research | July 1 - Sep 30, 2004 | PDF (399 kB) |
| QPR 9 | Intracochlear potentials evoked by electrical stimulation with phase-separated balanced biphasic pulses | Apr 1 - June 30, 2004 | PDF (691 kB) |
| QPR 8 | Representation of fine structure or fine frequency information with cochlear implants | Jan 1 - Mar 31, 2004 | PDF (120 kB) |
| QPR 7 | Combined use of DRNL filters and virtual channels | Oct 1 - Dec 31, 2003 | PDF (383 kB) |
| QPR 6 | Signal processing strategies for a closer mimicking of normal auditory functions | Jul 1 - Sep 30, 2003 | PDF (679 kB) |
| QPR 5 | Recent enhancements of the speech laboratory system | Apr 1 - Jun 30, 2003 | PDF (890 kB) |
| QPR 4 | Measurements of interaural timing difference | Jan 1 - Mar 31, 2003 | PDF (260 kB) |
| QPR 3 | Additional perspectives on speech reception with combined electric and acoustic stimulation | Oct 1 - Dec 31, 2002 | PDF (473 kB) |
| QPR 2 | Longitudinal studies of improvement in performance with early experience using binaural cochlear implants | Jul 1 - Sep 30, 2002 | PDF (382 kB) |
| QPR 1 | Pitch-matched and pitch-distinct electrode pairs in bilaterally implanted arrays | Apr 1 - Jun 30, 2002 | PDF (559 kB) |
Contract N01-DC-8-2105 (1998-2002)
| No. | Title | Date | Link |
| QPR FINAL | Some likely next steps in the further development of cochlear prostheses | Oct 1, 1998 - Mar 30, 2002 | PDF (849 kB) |
| QPR 13 | Cooperative electric and acoustic stimulation of the auditory periphery: Comparison of psilateral and contralateral implementations | Oct 1 - Dec 31, 2001 |
HTML PDF (243 kB) |
| QPR 12 | Further studies regarding benefits of binaural cochlear implants | Jul 1 - Sep 30, 2001 |
HTML PDF (574 kB) |
| QPR 11 | Further studies to evaluate combined electric and acoustic stimulation | Apr 1 - Jun 30, 2001 |
HTML PDF (585 kB) |
| QPR 10 | Development of new tools: Speech test materials from the TIMIT corpus, HRTF processing of speech and noise recordings, unified database of processor designs and study results | Jan 1 - Mar 31, 2001 |
HTML PDF (166 kB) |
| QPR 9 | Binaural cochlear implant findings: Summary of initial results with eleven subjects (also MakeMod, PulseMod, and TestMod utility documentation) | Oct 1 - Dec 31, 2000 |
HTML PDF (495 kB) |
| QPR 8 | Combined electric and acoustic stimulation of the same cochlea (also MusiCI documentation) | Jul 1 - Sep 30, 2000 |
HTML PDF (782 kB) |
| QPR 7 | Further studies to evaluate effects of changes in stimulus rate and envelope cutoff frequency for CIS processors | Apr 1 - Jun 30, 2000 |
HTML PDF (2.4 MB) |
| QPR 6 | Effects of changes in stimulus rate and envelope cutoff frequency for CIS processors | Jan 1 - Mar 31, 2000 | PDF (3.1 MB) |
| QPR 5 | Strategies for representing speech information with cochlear implants | Oct 1 - Dec 31, 1999 | PDF (10.4 MB) |
| QPR 4 | Speech reception with bilateral cochlear implants | Jul 1 - Sep 30, 1999 |
HTML PDF (110 kB) |
| QPR 3 | Effects of manipulations in mapping functions on the performance of CIS processors | Apr 1 - Jun 30, 1999 |
HTML PDF (231 kB) |
| QPR 2 | Measures of performance over time following substitution of CIS for CA speech processors | Jan 1 - Mar 31, 1999 |
HTML PDF (1.0 MB) |
| QPR 1 | Discrimination among electrodes and interaural timing and amplitude cues in three subjects with bilateral cochlear implants | Oct 1 - Dec 31, 1998 |
HTML PDF (452 kB) |
Contract N01-DC-5-2103 (1995-1998)
| No. | Title | Date | Link |
| QPR FINAL | New Directions in implant design | Aug 1, 1995 - Sep 29, 1998 | PDF (4.7 MB) |
| QPR 11 | Design of new speech test materials and comparisons with standard materials | Feb 1 - Apr 30, 1998 |
HTML PDF (159 kB) |
| QPR 10 | Effects of upward extension of the frequency range analyzed by CIS processors | Nov 1, 1997 - Jan 31, 1998 |
HTML PDF (1.0 MB) |
| QPR 9 | Development of the evoked potentials laboratory | Aug 1 - Oct 31, 1997 |
HTML PDF (268 kB) |
| QPR 8 | Relationships between temporal patterns of nerve activity and pitch judgments for cochlear implant patients | May 1 - Jul 31, 1997 |
HTML PDF (400 kB) |
| QPR 7 | High rate studies, Subject SR2 | Feb 1 - Apr 30, 1997 |
HTML PDF (317 KB) |
| QPR 6 | Intracochlear evoked potentials in response to pairs of pulses: Effects of pulse amplitude and interpulse interval | Nov 1, 1996 - Jan 31, 1997 |
HTML PDF (121 kB) |
| QPR 5 | Bilateral cochlear implants controlled by a single speech processor | Aug 1 - Oct 31, 1996 |
HTML PDF (184 kB) |
| QPR 4 | New laboratory stimulator system | May 1 - Jul 31, 1996 |
HTML PDF (409 kB) |
| QPR 3 | 22 electrode percutaneous study: Results for the first five subjects | Feb 1 - Apr 30, 1996 |
HTML PDF (203 kB) |
| QPR 2 | Number of channels and electrode selection; Advantages of multiple channels in cochlear implants | Nov 1, 1995 - Jan 31, 1996 | PDF (3.4 MB) |
| QPR 1 | Learning effects with extended use of CIS processors; Results for the first subject, 22 electrode percutaneous study; Upward extension of the analyzed frequency range | Aug 1 - Oct 31, 1995 | PDF (1.8 MB) |
Contract N01-DC-2-2401 (1992-1995)
| No. | Title | Date | Link |
| QPR FINAL | Importance of the patient variable in determining outcomes with cochlear implants, parametric studies with CIS processors, imprtance of processor fitting, "virtual channel" and "sharpened field" CIS processors, Nucleus percutaneous study, design for an inexpensive but effective cochlear implant system, representation of complex tones by sound processors for implanted auditory prostheses, temporal representations with cochlear implants | Aug 1, 1992 - Jul 31, 1995 | PDF (3.0 MB) |
| QPR 11 | Intracochlear evoked potentials for sustained electrical stimuli | Feb 1 - Apr 30, 1995 | PDF (1.5 MB) |
| QPR 10 | A channel-specific tool for analysis of consonant confusion matrices | Nov 1, 1994 - Jan 31, 1995 | PDF (747 kB) |
| QPR 9 | Strategies for repairing implant temporal representation distortions | Aug 1 - Oct 31, 1994 | PDF (914 kB) |
| QPR 8 | Further studies of complex tone perception by implant patients | May 1 - Jul 31, 1994 | PDF (3.7 MB) |
| QPR 7 | Temporal representations with cochlear implants: modeling, psychophysical, and electrophysiological studies | Feb 1 - Apr 30, 1994 | PDF (2.7 MB) |
| QPR 6 | Evaluation of VCIS processors | Nov 1, 1993 - Jan 31, 1994 | PDF (1.6 MB) |
| QPR 5 | Transfer and dissemination of CIS processor technology; Parametric and control studies with CIS processors | Aug 1 - Oct 31, 1993 | PDF (1.8 MB) |
| QPR 4 | Representation of complex tones by sound processors for implanted auditory prostheses | May 1 - Jul 31, 1993 | PDF (3.0 MB) |
| QPR 3 | Identification of virtual channel conditions on the basis of pitch | Feb 1 - Apr 30, 1993 | PDF (1.3 MB) |
| QPR 2 | Single parameter variation studies for CIS processors | Nov 1, 1992 - Jan 31, 1993 | PDF (638 kB) |
| QPR 1 | Virtual channel interleaved sampling (VCIS) processors (two electrode preliminary studies) | Aug 1 - Oct 31, 1992 | PDF (644 kB) |
Contract N01-DC-9-2401 (1989-1992)
| No. | Title | Date | Link |
| QPR FINAL | Comparison of CA and CIS processors for multichannel cochlear implants, additional aspects of CIS performance, evaluation of other promising strategies, auditory brainstem implant | May 1, 1989 - Jul 31, 1992 | PDF (1.9 MB) |
| QPR 12 | Completion of poor clinical outcomes series; Summary of overall studies with 11 Ineraid subjects; Auditory brainstem implant studies | Feb 1 - Apr 30, 1992 | PDF (1.7 MB) |
| QPR 11 | Efficacy of CIS processors for patients with poor clinical outcomes | Nov 1 1991 - Jan 31, 1992 | PDF (4.6 MB) |
| QPR 10 | Randomized update orders; Slow rate CIS implementations; Channel number manipulations; Evaluation of other promising strategies; Performance of CIS and CA processors in noise; Use and possible development of new test materials | Aug 1 - Oct 31, 1991 | PDF (4.7 MB) |
| QPR 9 | Evaluation of a prototype portable processor; Evaluation of components in the MiniMed cochlear prosthesis; Evaluation of automatic gain control; Preliminary studies of modulation perception; Measures of dynamic range for a variety of pulse durations and rates | May 1 - Jul 31, 1991 | PDF (3.6 MB) |
| QPR 8 | Importance of patient and processor variables in determining outcomes with cochlear implants | Feb 1 - Apr 30, 1991 | PDF (1.7 MB) |
| QPR 7 | A wearable speech processor platform for auditory research | Nov 1, 1990 - Jan 31, 1991 | PDF (2.7 MB) |
| QPR 6 | Parametric variations and the fitting of speech processors for single-channel brainstem prostheses | Aug 1 - Oct 31, 1990 | PDF (2.7 MB) |
| QPR 5 | Further evaluation of CIS processors | May 1 - Jul 31, 1990 | PDF (1.0 MB) |
| QPR 4 | Comparison of CA and CIS processors in tests with 8 Ineraid subjects | Feb 1 - Apr 30, 1990 | PDF (2.7 MB) |
| QPR 3 | Evaluations of alternative implementations of CIS, IP, and Peak-picker strategies; Finite-element model of radial bipolar field patterns in the electrically stimulated cochlea | Nov 1, 1989 - Jan 31, 1990 | PDF (2.3 MB) |
| QPR 2 | New levels of speech perception with cochlear implants; A computer interface for testing patients implanted with the Nucleus device | Aug 1 - Oct 31, 1989 | PDF (1.7 MB) |
| QPR 1 | Comparison of analog and pulsatile coding strategies for multichannel cochlear implants (6 UCSF/Storz subjects, 2 Ineraid subjects) | May 1 - Jul 31, 1989 | PDF (3.3 MB) |
Contract N01-NS-5-2396 (1985-1989)
| No. | Title | Date | Link |
| QPR FINAL | Direct comparisons of analog and pulsatile coding strategies, design and evaluation of a two-channel, "Breeuwer/Plomp" processor, additional processor comparisons, psychophysical studies, development of a next-generation auditory prosthesis | Sep 26, 1985 - Mar 31, 1989 | PDF (3.1 MB) |
| QPR 14 | Binary comparisons of speech processor performance | Dec 27, 1988 - Mar 26, 1989 | PDF (1.6 MB) |
| QPR 13 | Models of neural responsiveness to electrical stimulation | Sep 26 - Dec 26, 1988 | PDF 2.2 MB) |
| QPR 12 | Representations of speech features with cochlear implants | Jun 27 - Sep 26, 1988 | PDF (2.2 MB) |
| QPR 11 | Extension of cochlear implant laboratory capabilities; Development of a next-generation auditory prosthesis | Mar 26 - Jun 27, 1988 | PDF (621 kB) |
| QPR 10 | Review of clinical trial results for 6 UCSF/Storz subjects, including learning effects with extended use | Dec 28, 1987 - Mar 25, 1988 | PDF (925 kB) |
| QPR 9 | Studies with 6 UCSF/Storz subjects | Sep 27 - Dec 28, 1987 | PDF (2.4 MB) |
| QPR 8 | Evaluation of two channel "Breeuwer/Plomp" processors for cochlear implants | Jun 27 - Sep 26, 1987 | PDF (1.3 MB) |
| QPR 7 | A portable processor for IP processing strategies | Mar 26 - Jun 26, 1985 | PDF (4.5 MB) |
| QPR 6 | Direct comparison of analog and pulsatile coding strategies with six cochlear implant patients | Dec 26, 1984 - Mar 26, 1985 | PDF (2.0 MB) |
| QPR 5 | Studies of loudness and pitch perception with cochlear implants | Sep 26 - Dec 26, 1984 | PDF (5.9 MB) |
| QPR 4 | Evaluation of idealized Australian processors | Jun 26 - Sep 26, 1984 | PDF (3.4 MB) |
| QPR 3 | Initial development of a portable, real-time processor | Mar 27 - Jun 26, 1984 | PDF (1.2 MB) |
| QPR 2 | Studies with a second DUMC/Storz percutaneous subject | Dec 27, 1983 - Mar 26, 1984 | PDF (2.5 MB) |
| QPR 1 | Studies with an initial DUMC/Storz percutaneous subject | Sep 26 - Dec 27, 1983 | PDF (995 kB) |
Contract N01-NS-2356 (1983-1985)
| No. | Title | Date | Link |
| QPR FINAL | Hardware interface, computer-based simulator of speech processors, integrated field-neuron model, ensemble models of neural responses evoked by intracochlear electrical stimulation, design of a portable speech processor, evaluation of processing strategies in tests with patient LP | Sep 26, 1983 - Sep 26, 1985 | PDF (881 kB) |
| QPR 8 | Ensemble models of neural responses to intracochlear electrical stimulation | Jun 26 - Sep 26, 1985 | PDF (3.2 MB) |
| QPR 7 | Speech test studies with a UCSF/Storz subject; Present status and functional description of the block-diagram compiler | Mar 26 - Jun 26, 1985 | PDF (2.9 MB) |
| QPR 6 | Development of portable, real-time hardware; software for support of the RTI patient stimulator; Software for support of basic psychophysical studies and speech testing; Subject testing at UCSF | Dec 26, 1984 - Mar 26, 1985 | PDF (1.3 MB) |
| QPR 5 | Further development and application of a field neuron model | Sep 26 - Dec 26, 1984 | PDF (1.1 MB) |
| QPR 4 | Development of a component of a field neuron model of intracochlear electrical stimulation, a computer-based simulator of speech processors for multichannel auditory prostheses | Jun 26 - Sep 26, 1984 | PDF (2.8 MB) |
| QPR 3 | Hardware and software construction at RTI, further development of an integrated field-neuron model | Mar 27 - Jun 26, 1984 | PDF (476 kB) |
| QPR 2 | Model of field patterns produced by intracochlear electrodes | Dec 27, 1983 - Mar 26, 1984 | PDF (2.3 MB) |
| QPR 1 | Overview of project and planned collaborations | Sept 26 - Dec 27, 1983 | PDF (500 kB) |