Neglected Tropical Diseases

RTI is a global leader in neglected tropical disease (NTD) control and elimination. Since 2006, we have worked in close partnership with more than 20 NTD-endemic countries to help integrate and scale up their national programs for those NTDs that can be tackled with preventive chemotherapy (PC): lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma. Additionally, RTI staff members have technical expertise and implementation experience in dengue, leishmaniasis, dracunculiasis (Guinea worm), and Chagas disease prevention, control, and eradication.

Areas of Expertise

We offer expertise across the full range of interventions necessary for effective NTD control and elimination. Areas of expertise include

Learn more about RTI's projects, connect with our NTD networks, and find links to other NTD resources


Large-Scale NTD Programming

  • Population-based drug distribution—Working with national NTD programs to implement community- and school-based drug distribution, apply integrated strategies, training in mass drug administration, community mobilization, and protocols for serious adverse events
  • Lead implementation partner for ENVISION—In 2013 alone, RTI supported the distribution of over 152 million NTD treatments to over 77 million people as part of the USAID-funded ENVISION project

Morbidity Management and Disability Prevention

  • Strategic planning—Situational analyses for the three conditions (i.e., trichasis, hydrocele, and lymphedema), developing country-owned strategic plans
  • TOMS giving partner—Coordinated school-based distribution of shoes and NTD medicines

Monitoring and Evaluation

  • Completing an epidemiological map—Strategies for coordinated mapping and for prioritizing districts for mapping, partnering with the Global Trachoma Mapping Project to complete all trachoma mapping worldwide by 2015
  • Data quality assessments—Partnered with World Health Organization (WHO) to develop a protocol and the necessary tools to evaluate the quality of reported data and data management systems at different administrative levels of the health system; assessments have been implemented in Cameroon, Indonesia, and Uganda, with many more planned in 2014 and 2015
  • Integrated NTD database—Led the development of the integrated NTD database in partnership with WHO; database links seamlessly to WHO's Joint Reporting Form, the data reporting form for the African Program for Onchocerciasis Control, the Trachoma Elimination Monitoring Form, and the data acquisition tools for USAID
  • MDA data collection and review—Supports the full set of monitoring and evaluation tools used by USAID, tracking program performance and documenting impact
  • NTD Tool for Integrated Programming and Costing—Microsoft Excel-based tool for program planning and budgeting, facilitating coordinated action planning, funding gap analysis, and refining integrated national plans of action; available in English, French, Portuguese, Bahasa Indonesia, and Spanish; exports directly to the WHO Joint Reporting Form for donated medicines
  • Preparing countries for disease elimination—Working with NTD-endemic countries to plan and implement disease-specific assessments; training in transmission assessment surveys for lymphatic filariasis, impact surveys for trachoma, and diagnostics procurement

NTD Operational Research

Vector Control

  • Indoor residual spraying of households with insecticide (IRS)—Management of large-scale IRS operations, environmental compliance, entomological surveillance, and insecticide resistance monitoring
  • Insecticide-treated nets (ITNs)—Distribution of ITNs through various approaches, including through mass distribution, antenatal care clinics, and schools
  • Larviciding—Application of larvicides to insect-breeding sites
  • Joint control of malaria, lymphatic filariasis, and dengue—Entomological surveillance, capacity building for public health entomologists, and vector control specialists; building, equipping, and training staff for insectaries and mapping vectors

Past and Current Neglected Tropical Disease Projects

Morbidity Management and Disability Prevention for Blinding Trachoma and Lymphatic Filariasis (2014-2019), USAID—Capacity building of national programs to clear the backlog of trichiasis and hydrocele surgeries and to extend lymphedema management to community-based programs

NTD ENVISION Project (2011-2019), USAID—Technical and financial assistance to national NTD programs to manage and implement strategic control and elimination activities

Supplemental Vector Control to Facilitate Elimination of Lymphatic Filariasis: A Landscape Analysis (2013-2014), Bill & Melinda Gates Foundation (Gates Foundation)—Development of a lymphatic filariasis vector database and interactive map, specifying species composition and distribution of vector in endemic areas

Reinvent the Toilet Challenge (2012-2014), Gates Foundation—Development of waste treatment systems for areas with limitations on energy and water usage; designed and tested a waterless toilet that converts human waste into burnable fuel, stored energy, and disinfected, non-potable water

Millennium Water and Sanitation Program (2009-2014), USAID—Improved sustainable access to water supplies and sanitation and promoted better hygiene in targeted rural and peri-urban areas of Senegal

Integrated Vector Management (IVM) Project (2007-2012), USAID—Institutional strengthening and capacity building for IVM of malaria and other vector-borne diseases such as dengue, lymphatic filariasis, and leishmaniasis; applied research, IVM training development, and best practices

NTD Control Program (2006-2012), USAID—Technical and financial assistance for 19 national NTD programs in the implementation of integrated approaches for scale up of preventive chemotherapy for lymphatic filariasis, schistosomiasis, trachoma, onchocerciasis, and three soil-transmitted helminths

Environmental Health Project (2004-2009), USAID—Environmental, behavioral, and policy interventions to prevent infectious diseases—including NTDs—caused by environmental conditions

Member Global NTD Networks

NTD Resources


people-photo Richard Reithinger
Vice President, Global Health
people-photo Lisa Rotondo
Project Director, ENVISION
people-photo Amy Doherty
Deputy Director, ENVISION
people-photo Achille Kabore
Senior Advisor, Neglected Tropical Diseases, ENVISION
people-photo Margaret Cameron Baker
Senior Manager, Knowledge Management
people-photo Philip Downs
Senior Manager, Neglected Tropical Diseases, ENVISION
people-photo Jeremiah Ngondi
Senior Epidemiologist, Tanzania Vector Control Scale-up Project (TVCSP)