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Hernan Navarro

Hernan Navarro
Hernan Navarro

Expertise

Neuropharmacology; Neuroanatomy; In Vitro Pharmacology; Biochemistry of Addiction

Biography

Hernan Navarro is director of pharmacology and toxicology in chemistry and life sciences. He has over 20 years of experience in CNS pharmacology, with research ranging from the effects of in utero exposure to cholinomimetics on offspring brain and immune function development to the in vitro and in vivo characterization of radioligands and the pharmacological characterization of novel orthosteric or allosteric CNS-active compounds. He has extensive experience with cell culture and in vitro assay techniques such as FLIPR, 96-well-based phenotypic assays, radioligand binding, and synaptosomal uptake or release of radiolabeled compounds. Dr. Navarro also has experience with neurobehavioral techniques such as Morris water maze, locomotor activity, and auditory startle. He is currently interested in establishing non-mammalian behavioral assays for use in drug discovery and toxicology.

Education

NRSA Postdoctoral Fellow and Research Associate, Pharmacology, Duke University Medical Center; PhD, Human Anatomy, University of Kentucky; BS, Botany, Duke University.

Selected Publications

Navarro, H.A., Gilmour, B.P., & Lewin, A.H. (2006). A rapid functional assay for the human trace amine-associated receptor 1 based on the mobilization of internal calcium. Journal of Biomolecular Screening , 11 (6):688-693.
Navarro, H., Basta, P., Seidler, F., & Slotkin, T. (2003 Nov). Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: Critical periods, patterns of exposure, dose thresholds. Nicotine and Tobacco Research, 5 (6):859-868.
Navarro, H.A., Xu, H., Zhong, D., Abraham, P., & Carroll, F.I. (2002). In vitro and in vivo characterization of [I-125]iodomethyllycaconitine in the rat. Synapse, 44 (3):117-123.

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