The personalized medicine field presents a new paradigm in healthcare and the treatment of disease. North Carolina has a number of leaders in this emerging field – represented by researchers and scientists at its preeminent universities, laboratories and research institutes, as well as its biotechnology and pharmaceutical companies. Among the subjects to be explored by a field of local, national and international experts will be a concept gaining momentum called "P4," which uses treatment tools that are "Predictive, Preventive, Personalized, and Participatory."

8:15 a.m.—Welcome and Introductions

• Jennie Hunter-Cevera, PhD, Conference Co-Chair, Executive Vice President, Discovery & Analytical Sciences, RTI International
• Norris Tolson, President, North Carolina Biotech Center

8:30 a.m.—Keynote Address: Funding and Investment Perspective

"Value Creation in Personalized Medicine: Is There Enough Capital? And Are Company Business Models Sustainable?"

Introduction

• Michael Luther, President, David H. Murdock Research Institute

Keynote Speaker

• G. Steven Burrill, CEO, Burrill & Company

9:30 a.m.—Panel Discussion: Public Policy Perspective

"Government's Role in Making Personalized Medicine Measurable and Meaningful: Initiatives, Incentives and Standards"

Introduction

• Terri L. Lomax, Vice Chancellor for Research and Graduate Studies, North Carolina State University

Moderator

• Don Bailey, PhD, Distinguished Fellow, RTI International

Panelists

• Michael Amos, PhD, BioSciences Advisor to the Director, National Institute for Standards and Technology (NIST)
• Vicki Seyfert-Margolis, PhD, Senior Advisor for Science Innovation and Policy, Office of the Commissioner, U.S. Food and Drug Administration (FDA)
• Steven McPhail, CEO, Expression Analysis

10:45 a.m.—Coffee Break

11:15 a.m.—Keynote Address: Scientific Perspective

"The Future of Genomic and Personalized Medicine: Foundations and Applications"

Introduction

• James N. Siedow, Vice Provost for Research, Duke University

Keynote Speaker

• Geoffrey Ginsburg, MD, PhD, Director, Center for Genomic Medicine & Executive Director, Center for Personalized Medicine, Duke University

12:15 p.m.—Luncheon and Keynote Address: International Perspective

"Metabolism-Directed Systems Biology Approaches to Personal and Public Health Problems"

Introduction

• Victoria Haynes, PhD, President, RTI International

Keynote Speaker

• Jeremy Nicholson, PhD, Professor, Department of Biomolecular Medicine at Imperial College, London, and Chair of Biological Chemistry, Division of Surgery, Oncology and Reproductive Biology

1:45 p.m.—Panel Discussion: Functional Perspective

"The Multidisciplinary Approach to Personalized Medicine: Fitting Together the Pieces of the 'P-4' Puzzle (Predictive, Preventive, Personalized, and Participatory)"

Introduction

• Catherine Innes, Director, Office of Technology Development, University of North Carolina–Chapel Hill

Moderator

• Jennie Hunter-Cevera, PhD, Conference Co-Chair, Executive Vice President, Discovery and Analytical Sciences, RTI International

Panelists

• Nathan Price, PhD, University of Illinois Institute for Genomic Biology
• Clay Marsh, MD, Executive Director, Center for Personalized Health Care, Ohio State University
• Karen Weck, MD, Director, Molecular Genetics Laboratory; Associate Director, Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina–Chapel Hill
• Lee Mobley, PhD, Senior Fellow, Health Economics, RTI International
• Susan Sumner, PhD, Senior Scientist, RTI International

3:00 p.m.—Panel Discussion: Future Prospects

"Potential Stumbling Blocks Along the Road: Comparative Effectiveness, Reimbursements, and Biomarkers as Intellectual Property"

Moderator

• Steven Casey, Vice President, Statewide Operations, North Carolina Biotechnology Center

Panelists

• Amy Abernethy, MD, Program Director, Duke Cancer Care Research Program and representative of Personalized Medicine Coalition
• Steven Hultquist, Founder & Principal, Intellectual Property & Technology Law
• Paul M. Brown, PhD, Research Associate Professor, Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill

4:00 p.m.—Closing Remarks

• Jennie Hunter-Cevera, PhD, Executive Vice President, Discovery & Analytical Sciences, RTI International

Closing Reception