Neglected Tropical Diseases

More than one billion people worldwide are affected by one or more neglected tropical diseases (NTDs). These diseases disproportionately impact poor and rural populations who lack access to safe water, sanitation, and essential medicines. They cause sickness and disability, compromise maternal health and fetal growth, inhibit children's mental and physical development, and can result in blindness and severe disfigurement.

Working Towards 2020 Goals for NTD Control and Elimination

RTI is a global leader in NTD control and elimination. Since 2006, RTI has worked with US Agency for International Development (USAID) support in partnership with NTD endemic countries in Africa, Latin America, and Asia to integrate and expand their national NTD control programs for lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma. We have expertise in integrated NTD control program management and implementation, integrated strategic planning and costing, disease mapping, surveillance, and monitoring and evaluation (M&E). In addition, we contribute to the global policy dialogue on integrated NTD control, participating in multiple World Health Organization (WHO) Advisory and Working Groups on NTDs.

International Training Course for NTD Program Managers

We have worked with WHO to develop a comprehensive course on integrated NTD control for program managers from NTD endemic countries. The first of its kind, this course features critical components of integrated NTD strategies, including implementation techniques, program management principles, drug and severe adverse event management, M&E, planning and costing analysis, and advocacy strategies to garner long-term support.

Monitoring and Evaluation of Integrated PCT for NTD Control

We have contributed to the design and establishment of international M&E standards and guidelines for the seven NTDs that PCT addresses. Having developed tools to monitor and track integrated mass drug administration (MDA) coverage and progress towards elimination, we are working in close collaboration with WHO and USAID to develop an M&E Framework with a compendium of indicators, which will assist in harmonizing data management practices across country programs and NTD partners.

Tool for Integrated Planning and Costing (TIPAC)

The Tool for Integrated Planning and Costing (TIPAC) was developed by RTI as a key component of the NTD Rollout Package adopted and promoted by WHO and USAID to help countries develop an integrated program for NTDs. It can be used in conjunction with existing national NTD strategic plans and budgets in order to plan and coordinate future program resources effectively.

NTD Projects


RTI is the prime contractor for USAID's ENVISION project (2011-2016), aimed at providing assistance to national NTD control programs for the control and elimination of seven targeted NTDs: lymphatic filariasis, onchocerciasis, schistosomiasis, three soil-transmitted helminths (roundworm, hookworm, whipworm), and trachoma. ENVISION contributes to several activity areas for the control and elimination of the seven targeted NTDs, including

  • Support for NTD program implementation led by Ministries of Health
  • Drug and diagnostics procurement where donation programs are unavailable
  • Capacity building (in coordination with WHO, USAID, and global partners)
  • Management and implementation of the technical assistance facility
  • Disease mapping (in coordination with WHO, USAID, and global partners)
  • NTD policy development (in coordination with WHO, USAID, and global partners)
  • NTD monitoring and evaluation (in coordination with WHO, USAID, and global partners)

ENVISION is implemented in partnership with CBM International, The Carter Center, Helen Keller International, IMA World Health, Tulane University, Sightsavers International, and World Vision.

NTD Control Program

RTI served as the prime contractor for USAID's NTD Control Program (2006-2012), the first global effort to integrate and scale up delivery of preventive chemotherapy for lymphatic filariasis, onchocerciasis, schistosomiasis, trachoma, and soil-transmitted helminths. The NTD Control Program supported national NTD control programs in 13 countries and provided short-term technical assistance in an additional six countries. Over 100 million people were treated with USAID NTDCP support at least once throughout the six years of project implementation, supporting the distribution of over 500 million treatments for NTDs.

More Information


Nigeria Launches Plan to Control Neglected Tropical Diseases
Neglected tropical diseases research

Nigeria has launched a five-year NTD Master Plan aimed at controlling neglected tropical diseases. RTI International and... Read more »


Richard Reithinger
Senior Director, Global Health
Eric A. Ottesen
Project Director, ENVISION