International Epidemiology
We have conducted extensive epidemiologic research throughout the world, with emphasis on work in developing countries. Special considerations and precautions need to be addressed when conducting studies outside of the United States. Cultural differences impact the types of data that can be collected and how social roles influence expectations, norms, and behaviors. In addition, labor regulations and other legal requirements, import tariffs, appropriate labor rates, and use of foreign currency add a high level of complexity when setting up foreign subcontracts. Our experienced, committed staff anticipate potential obstacles, mitigate problems that arise, and ensure high-quality and efficient study performance.
Focus Areas
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Transmission of HIV to partners and infants
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Chronic disease outcomes of viral infections (e.g., AIDS, cancer, liver disease)
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Community-level intervention to modify HIV/AIDS risk behaviors
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Women’s and children’s health and pregnancy outcomes
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Malaria
Capabilities
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IT and scientific technology resource evaluation and solutions
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Data collection (clinical, laboratory, and personal)
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Biospecimen export from countries with restricted policies
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Development and evaluation of laboratory and biorepository facilities and staff
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Design and implementation of quality control procedures
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Hiring and training of field staff
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Ethics committee approvals
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Development of materials and procedures that are culturally appropriate and effective
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Foreign language translations
Projects
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Preparing and Performing Readiness Assessment(s) for Implementation of New Biomedical HIV Prevention Technologies in the Republic of South Africa (2011–2012). The United States Centers for Disease Control and Prevention, South Africa, in collaboration with RTI International and Health Systems Trust, is leading a project to develop a tool for assessing site readiness to provide oral and vaginal pre-exposure biomedical prophylaxis in public health facilities in South Africa. These tools will help to facilitate the implementation of PrEP, in anticipation of positive research results and regulatory approval.
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Technical Assistance Consortium for the CDC Center for Global Health (2010–2015). Technical assistance, capacity building, and workforce training for the Centers for Disease Control and Prevention's Center for Global Health in support of its mission to eradicate disease and improve health care delivery worldwide, with a focus on program activities, business services and training. For more information, download the project brochure.
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Epidemiology of Burkitt's Lymphoma in East African Children or Minors (EMBLEM) (2008–2012). A prospective case-control study to investigate whether having genetic resistance to malaria is protective for endemic Burkitt’s lymphoma (BL). A secondary objective is to explore spatial and/or seasonal clustering of endemic BL in Uganda using GIS and remotely collected data to explore and generate new hypotheses about local environmental factors associated with endemic BL.
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International Consortium for Applied Radiation Research (2006–2008). A cohort study of workers constructing the new containment structure for the damaged Chernobyl Nuclear Power Plant to identify genetic and metabolic markers related to varying levels of radiation exposure over time and the potential human health impacts of exposure.
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Health Surveillance Research in Foreign Military Populations (2005–2013). HIV seroprevalence and behavioral epidemiology risk survey among foreign military members in participating Department of Defense HIV/AIDS Prevention Program nations, including Botswana, Ethiopia, the Gambia, Lesotho, Mozambique, South Sudan, Swaziland, and Uganda. For more information, download the project brochure.
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Population Genetics of Immune Response: Typhoid and Cholera Vaccine (2004–2008). A study in India that aims to discover and characterize associations between human immune response gene polymorphisms and the outcomes of infection or vaccination for pathogens (cholera, typhoid) of primary interest for biodefense.
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Data Coordinating Center for a Randomized Controlled Trial of Male Circumcision to Reduce HIV Incidence in Kisumu, Kenya (2002–2008). An unblinded, randomized trial of HIV incidence after 24 months of follow-up in two groups: the treatment or circumcision arm, and the control or uncircumcised arm.
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Global Network for Women’s and Children’s Health Research (2001–2012). A collaborative effort of international, multidisciplinary teams of investigators working to prevent disease and premature death of women and children in developing countries and to develop research capacity at local foreign organizations and institutions.
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Collaborative HIV/STD Prevention Trial (1999–2008). A two-arm randomized trial examining the efficacy of a community-level intervention to reduce HIV/STD incidence and high-risk behaviors in China, India, Peru, Russia and Zimbabwe sentence description. Also see Collaborative HIV/STD Prevention Trial brochure.
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Multicenter Hemophilia Cohort Studies (1986–2005). A series of international longitudinal studies at 54 clinical sites designed to address emergent issues associated with hemophilia and viral infections, including the transmissions of HIV, HBV and HCV and the development of AIDS, non-Hodgkin’s lymphoma, other cancers and liver diseases.
Contact us for more information
- Mary-Anne E. Ardini-Poleske
- Lisa C. Strader