Genomics and Molecular Epidemiology
We are pioneering research in the study of genes and gene sequences (genomics) by collaborating across our internal research centers as well as reaching outside to education and industry. Our staff collect environmental samples and use state-of-the-art laboratories to measure contaminants and biomarkers and to assess gene-environment interactions. We work closely with our clients to address the specific needs of each study.
Focus Areas
- Children's health
- Environmental assessments
- Social and economic effects of genomics
- Substance abuse
Capabilities
- Collection of genotype and phenotype data
- Data collection
- Field protocol preparation
- Instrument preparation
- Measurement of gene and protein expression
- Measurement of genetic variation
- Procedural manual development
Projects
- Population Genetics Analysis Program: Immunity in Response to Typhoid/Cholera Vaccines. We are conducting research on innate and adaptive immunity genes associated with response to typhoid and cholera vaccines and the consequent protein expression. State-of-the-art techniques in genomics and proteomics will be used to study the response longitudinally to vaccination in a large ethnic population in India, in which these gastrointestinal tract infections are endemic.
- National Long-Term Care Survey. This study is funded by the National Institute on Aging, which involves gathering genetic samples along with health interviews of the elderly. The specimens in this study of functional and health changes among the elderly are being used to identify specific genetic markers and their relationship with cognitive impairment, dementia, and diseases associated with aging in a national sample of elderly respondents.
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