• Genetics, Proteomics, & Bioinformatics
• Genomics & Molecular Epidemiology
• Proteomics
• Statistical Genetics & Bioinformatics

Genetics, Proteomics, and Bioinformatics Research

The rapidly evolving science of biotechnology is helping to unlock the mysteries of cell activity, genetic coding, and human disease. We use state-of-the-art laboratory and statistical tools, combined with research expertise across multiple disciplines, in our related studies of genetics, proteomics, and bioinformatics. As multidisciplinary genetic studies break new ground, our researchers collaborate outside RTI to strengthen and broaden these fields of research.

Focus Areas

• Genomics and Molecular Epidemiology
  Children's health; environmental assessments; social and economic effects of genomics; substance abuse
• Proteomics
  MS technology development for biothreat agent detection; explosives analysis by MS; quantitative analysis of bioactive peptides; structural confirmation/purity assessment of synthetic peptide analogues; analysis/sequence confirmation of recombinant proteins; proteome profiling of hyperthermophilic bacteria; determination of protein turnover profiles by MS
• Statistical Genetics and Bioinformatics
  Clinical trials; natural history studies of disease progression; epidemiological research on incidence, prevalence, risk factors, and causes of diseases; health promotion and disease prevention research; environmental toxins
• Disease immunity
• Environmental toxins, their movement through the food web, and their effect at the genetic level
• Health promotion and disease prevention research
• Measurement of genetic variation

Capabilities

• Analysis and design of clinical trials with a genetic/genomics component
• Analysis/sequence confirmation of recombinant proteins
• Development and use of statistical methods for bioinformatics
• Mass spectrometry technology development for bio-threat agent detection
• Regulatory issues relating to biotechnology