Drug Discovery
Our drug discovery group specializes in cancer and central nervous system drug research. Several major products including Taxol have been discovered at RTI, and we currently have several compounds in clinical trials. Our drug discovery team has expertise in pharmacology, synthetic chemistry, modeling, analytical, and identification techniques. Our extensive laboratory facilities give us the ability to support multiple client projects to satisfy our clients' drug discovery programs.
Focus Areas
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Chemical Synthesis and Characterization
Camptothecins, cannabinoids, morphans, phenylamines, steroids, tropanes -
Pharmacology and Bioassays
Central nervous system pharmacology; cystic fibrosis; molecular biology -
Chemoinformatics
Electronic databases describing the chemistry, biology, and effects of compounds from more than 40 years of synthetic and natural products chemistry at RTI
Capabilities
- Traditional, rational drug design methodologies
- Combinatorial/array methodologies
- Radiosynthesis
- Nuclear magnetic resonance
- Array synthesis
Science and the War on Designer Drugs
With funding from the National Institute on Drug Abuse, RTI scientists are applying their expertise to help address the global challenge of clandestinely produced drugs that are pharmacologically similar to a controlled substance but are not illegal.