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Drug Discovery

Brian Thomas is searching for promising new compounds with therapeutic effects.

Our drug discovery group specializes in cancer and central nervous system drug research. Several major products including Taxol have been discovered at RTI, and we currently have several compounds in clinical trials. Our drug discovery team has expertise in pharmacology, synthetic chemistry, modeling, analytical, and identification techniques. Our extensive laboratory facilities give us the ability to support multiple client projects to satisfy our clients' drug discovery programs.

Focus Areas

  • Chemical Synthesis and Characterization
    Camptothecins, cannabinoids, morphans, phenylamines, steroids, tropanes
  • Pharmacology and Bioassays
    Anticancer and central nervous system pharmacology; cystic fibrosis; molecular biology
  • Chemoinformatics
    Electronic databases describing the chemistry, biology, and effects of compounds from more than 40 years of synthetic and natural products chemistry at RTI
  • Natural Products Research
    Bioactive compounds in plants, bacteria, and fungi; anticancer, antifungal, antibacterial, and central nervous system drug discovery; herbal supplements and their interactions with cancer and conventional cancer treatments

Capabilities

  • Traditional, rational drug design methodologies
  • Combinatorial/array methodologies
  • Radiosynthesis
  • Nuclear magnetic resonance
  • Array synthesis

Contact us for more information

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UMBI President Jennie Hunter-Cevera to Join RTI International as Executive Vice President of Discovery and Analytical Sciences, Corporate Development

Jennie Hunter-Cevera

Jennie Hunter-Cevera, Ph.D., a distinguished scientist, business leader and the current president and CEO of the University of Maryland Biotechnology Institute (UMBI), will join RTI International July 1, as Executive Vice President of Discovery and Analytical Sciences and Corporate Development.

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