January 10, 2013

New Book Discusses Contemporary Practices of Toxicology

Highlights

  • The Clinical Toxicology Laboratory, 2nd Edition, discusses the wide range of disciplines representative of the essence of contemporary toxicology practices
  • Four RTI International researchers are contributing authors to the volume
  • The book explores the practice and teaching of toxicology in the current clinical laboratory environment

Media Contacts

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  • Lisa Bistreich-Wolfe
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  • Kami Spangenberg
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RESEARCH TRIANGLE PARK, N.C. -- A new book discusses the wide range of disciplines representative of the essence of contemporary toxicology practices.

The Clinical Toxicology Laboratory, 2nd Edition, contains valuable, state-of-the-art information that explores the practice and teaching of toxicology in the current clinical laboratory environment. Four RTI International researchers are contributing authors to the volume.

The book includes dramatic advances in the care of the poisoned patient, the advent of regional poison centers, and the successful efforts of clinical laboratories to adapt new and effective technologies to support changing diagnostic and treatment modalities.

Jeri D. Ropero-Miller, Ph.D., co-authored a chapter on opioids, which gives an introduction to these drugs, and discusses the therapeutic indications, pharmacology, pharmacokinetics and toxicology of opioid analgesics.

Ropero-Miller is a senior forensic scientist of the Center of Forensic Sciences at RTI. She has more than 15 years of experience in conducting forensic toxicology, clinical chemistry and studies in drug testing of hair. She is a board-certified forensic toxicologist with Diplomate status in the American Board of Forensic Toxicology. She is also a contributing author to the recently-published book, Forensic Science: Current Issues, Future Directions.

The Clinical Toxicology Laboratory's chapter on advanced analytical techniques was co-written by RTI researchers Peter R. Stout, Ph.D; Megan Grabenauer, Ph.D.; and Brian F. Thomas, Ph.D.  

The chapter explores the advanced analytical techniques currently used in toxicology and therapeutic drug monitoring to increase the information available about the identity of an unknown compound, to improve the specificity of detection, or to improve limits of detection for trace concentration compounds.

Stout has more than 15 years of experience in forensic urine drug testing, postmortem toxicology and human performance testing laboratories.

He is vice president for the Society of Forensic Toxicologists, an American Academy of Forensic Sciences fellow, and the past chair of the Toxicology Section of AAFS. Additionally, Stout serves as a laboratory inspector for the National Laboratory Certification Program and for the American Board of Forensic Toxicology.

Grabenauer has extensive experience in biophysical techniques for the study of proteins and small molecules, with an emphasis in mass spectrometry. She has been published extensively and has given presentations on chemistry and toxicology to international audiences, and was recently invited to speak as a scientific expert at the European Commission’s Workshop on Designer Drugs in Berlin. Grabenauer currently serves as principal investigator for a project related to basic research in forensic science funded by the National Institute of Justice.

Thomas is the director of Analytical Chemistry and Pharmaceutics at RTI. He has more than 25 years of experience in analytical chemistry and mass spectrometry. He is the primary investigator or co-primary investigator on several contracts with the National Institute on Drug Abuse for formulation development and manufacturing, analytical characterization and specification, and storage and distribution.

The Clinical Toxicology Laboratory is published by AACC Press and is available on leading commercial bookseller websites.


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Experts

Peter R. Stout
Senior Research Forensic Scientist
Brian F. Thomas
Director, Analytical Chemistry and Pharmaceutics