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William Zule

Fellow, Senior Health Analyst

William Zule, DrPH, is a leading expert in community-based HIV prevention research. For more than 25 years, his research has focused on HIV and hepatitis C virus epidemiology and prevention.

Dr. Zule’s work suggests that better syringe designs may substantially reduce HIV infections from syringe sharing. He is currently working with two needle and syringe programs in Tajikistan to develop and test strategies for implementing the World Health Organization’s recommendations regarding the distribution of low dead space syringes to reduce hepatitis C virus and HIV transmission among people who inject drugs.

His early work helped clarify the context of indirect needle sharing in HIV risk among intravenous drug users. Dr. Zule has been a principal investigator, project director, and ethnographer on several large HIV prevention epidemiologic research projects. More recently, he has published a series of papers examining and assessing treatment readiness and entry among out-of-treatment drug users. Dr. Zule currently serves on the board of directors of the North Carolina Harm Reduction Association.


DrPH, University of Texas School of Public-Houston; MPH, University of Texas School of Public Health-Houston; BA, University of Texas-San Antonio.

Latest Publications

Kirtadze, I., Otiashvili, D., O'Grady, K., Zule, W., Krupitsky, E., Wechsberg, W., et al. (2015). Women who inject drugs in the Republic of Georgia: In their own words. Journal of Psychoactive Drugs, 47 (1):71-79.
Zule, W., Myers, B., Carney, T., Novak, S.P., McCormick, K., & Wechsberg, W.M. (2014). Alcohol and drug use outcomes among vulnerable women living with HIV: Results from the Western Cape Women's Health CoOp. AIDS Care, 26 (12):1494-1499.
Latypov, A., Otiashvili, D., & Zule, W. (2014). Drug scene, drug use and drug-related health consequences and responses in Kulob and Khorog, Tajikistan. International Journal of Drug Policy, 25 (6):1204-1214.
Wechsberg, W.M., Zule, W.A., Ndirangu, J., Kline, T.L., Rodman, N.F., Doherty, I.A., Novak, S.P., et al. (2014). The biobehavioral Women's Health CoOp in Pretoria, South Africa: Study protocol for a cluster-randomized design. Biomed Central Public Health, 14 :1074.
Jones, H.E., Kirtadze, I., Otiashvili, D., O'Grady, K.E., Murphy, K., Zule, W., Krupitsky, E., & Wechsberg, W.M. (2014). Process and product in cross-cultural treatment research: Development of a culturally sensitive women-centered substance use intervention in Georgia. J Addict , 2014 :Article No. 163603.
View all publications by William Zule (84)


  • Injection Drug Users
  • HIV/HCV Epidemiology and Prevention
  • Methamphetamine Use
  • Substance Abuse Treatment Readiness