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Carla J. DeMuro-Mercon

Senior Research Psychometrician

Carla DeMuro-Mercon has extensive experience in the rigorous development and validation of patient-reported outcome measures for use in clinical trials as well as large-scale epidemiologic and population-based studies. Ms. DeMuro-Mercon has worked to developed measures across a wide span of therapeutic areas including respiratory illness (asthma, COPD, allergic rhinitis, influenza), oncology (non-small cell and small cell lung cancer), Alzheimer's disease, infectious disease (including sexually transmitted disease), sleep disorders, hair loss (male and female), menopausal symptoms, cognition, acne, benign prostatic hyperplasia, diabetes and migraine. Measures have included multiple types of patient-reported outcomes including quality of life, treatment satisfaction, symptom severity, daily event logs, patient diaries, utility measures and other patient-reported outcomes. She has specialized in both the qualitative and quantitative aspects of instrument design and has worked towards creating a clear path from measure development to interpretation.


PhD candidate, Public Health, Walden University; MS, Community Health, Arcadia University; BS (summa cum laude), Applied Computer Science/Communications, Chestnut Hill College.

Latest Publications

Assessment of PRO label claims granted by the FDA as compared to the EMA (2006–2010) — Value in Health
DeMuro, C., Clark, M., Doward, L., Evans, E., Mordin, M., & Gnanasakthy, A. (Dec 2013)
Influence of Patient-Reported Outcomes on Hta Reimbursement Decisions — Value in Health
Kulich, K., Versoza, L., Jaksa, A., Demuro-Mercon, C., & Gnanasakthy, A. (Nov 2013)
Patient-Reported Outcomes: Are They Worth It? An Examination in Pro Value Through Case Studies — Value in Health
DeMuro, C., & Gnanasakthy, A. (Nov 2013)
Proxy-reported questionnaires for young children with asthma: A structured review — European Respiratory Journal
Barrett, A., Clark, M., DeMuro, C., & Esser, D. (Aug 2013)
US FDA patient-reported outcome guidance: Great expectations and unintended consequences — Expert Review of Pharmacoeconomics & Outcomes Research
Fehnel, S., DeMuro, C., McLeod, L., Coon, C., & Gnanasakthy, A. (Aug 2013)
View all publications by Carla J. DeMuro-Mercon (32)