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Carla J. DeMuro-Mercon

Senior Research Psychometrician

Carla DeMuro-Mercon has extensive experience in the rigorous development and validation of patient-reported outcome measures for use in clinical trials as well as large-scale epidemiologic and population-based studies. Ms. DeMuro-Mercon has worked to developed measures across a wide span of therapeutic areas including respiratory illness (asthma, COPD, allergic rhinitis, influenza), oncology (non-small cell and small cell lung cancer), Alzheimer's disease, infectious disease (including sexually transmitted disease), sleep disorders, hair loss (male and female), menopausal symptoms, cognition, acne, benign prostatic hyperplasia, diabetes and migraine. Measures have included multiple types of patient-reported outcomes including quality of life, treatment satisfaction, symptom severity, daily event logs, patient diaries, utility measures and other patient-reported outcomes. She has specialized in both the qualitative and quantitative aspects of instrument design and has worked towards creating a clear path from measure development to interpretation.


PhD candidate, Public Health, Walden University; MS, Community Health, Arcadia University; BS (summa cum laude), Applied Computer Science/Communications, Chestnut Hill College.

Latest Publications

Winnette, R., Zarate, V., Machnicki, G., DeMuro, C., Gawlicki, M., & Gnanasakthy, A. (2015). Patient-reported outcomes in Latin America: Implementation in research and role in emerging HTA systems. Value in Health Regional Issues, 8 :49-55.
Hogue, S., Brogan, A.P., DeMuro, C., D'Alessio, D., & Bal, V. (2015). Patient Reported Outcomes (Pro) in Postprogression Oncology: Implications in Health Technology Assessments (Hta) & Payer Decision Making, Value in Health, 18 (7):A487-A488.
DeMuro, C., Williams, V., Goldberg, R., Lowes, L., Price, M., Capkun, G., et al. (2015). Resource utilization in a US-based sample of patients with sporadic inclusion body myositis (sIBM), Neuromuscular disorders : NMD, 25 :S238-S238.
DeMuro, C., Lewis, S., Lowes, L.P., Alfano, L., Tseng , B., & Gnanasakthy, A. (2015). A novel measure to assess self-reported physical functioning in patients with sporadic inclusion body myositis (Sibm), Value in Health, 18 (3):A286-A286.
Gnanasakthy, A., DeMuro, C., Lewis, S., & Tseng , B. (2015). Development of a disease model for sporadic inclusion body myositis (Sibm), Value in Health, 18 (3):A28-A29.
View all publications by Carla J. DeMuro-Mercon (46)


  • Instrument Development and Validation
  • Epidemiology