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Patricia Tennis

Global Head of Epidemiology, RTI-HS

Patricia Tennis, PhD, came to RTI in 2002 from the pharmaceutical industry, where she helped design and implement drug safety studies and risk management activities related to use of medications. She has focused on drug safety, collaborating on studies of vaccine safety and on safety studies of medications in neurology, psychiatry, respiratory, and metabolic diseases. She has overseen numerous epidemiology studies and participated in regulatory discussions of drug safety issues with U.S., Canadian, and European agencies. Dr. Tennis has been the lead epidemiologist on studies that required implementation of a common protocol across multiple patient-centric databases, international pregnancy exposure registries, and projects to evaluate risk evaluation and minimization strategies. She is a leading researcher in pharmacoepidemiology and a fellow of the International Society for Pharmacoepidemiology.


MPH, Epidemiology, University of North Carolina at Chapel Hill; PhD, Biology, Case Western Reserve University; MS, Biology, Case Western Reserve University; BS, Zoology, University of Wisconsin.

Latest Publications

Andrews, E.B., Margulis, A.V., Tennis, P., & West, S.L. (2014). Opportunities and challenges in using epidemiologic methods to monitor drug safety in the era of large automated health databases. Current Epidemiology Reports, 1 (4):194-205.
Mines, D., Tennis, P., Curkendall, S.M., Li, D.-.K., Peterson, C., Andrews, E.B., Calingaert, B., Chen, H., Deshpande, G., Esposito, D.B., Everage, N., Holick, C.N., Meyer, N.M., Nkhoma, E.T., Quinn, S., Rothman, K.J., et al. (2014). Topiramate use in pregnancy and the birth prevalence of oral clefts. Pharmacoepidemiology and Drug Safety, 23 (10):1017-1025.
Sinclair, S., Cunnington, M., Messenheimer, J., Weil, J., Cragan, J., Lowensohn, R., Yerby, M., & Tennis, P. (2014). Advantages and problems with pregnancy registries: observations and surprises throughout the life of the International Lamotrigine Pregnancy Registry. Pharmacoepidemiology and Drug Safety, 23 (8):779-786.
Andrews, E.B., Davis, K.H., DiBenedetti, D.B., Forsyth, B.H., Gilsenan, A.W., Hollis, K.A., Lewis, S.A., Price, M.A., Tennis, P.S., & Zografos, L.J. (January 2014). Risk evaluation and mitigation strategy assessments: Social science methodologies to assess goals related to knowledge: RTI Press Publication No. OP-0018-1401. Research Triangle Park, NC: RTI Press.
Riera-Guardia, N., Saltus, C.W., Bui, C.L., Harris, D.H., Kaye, J.A., Tennis, P., Castellsague, J., & Perez-Gutthann, S. (August 2013). Changes in the landscape of health care database research from 2000 to 2011: RTI Press Publication No. RR-0019-1308. Research Triangle Park, NC: RTI Press.
View all publications by Patricia Tennis (58)


  • Therapeutic Outcomes and Safety
  • Drug Safety
  • Pharmacoepidemiology