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Jenny L. Wiley

Senior Fellow, Behavioral Pharmacology

Jenny Wiley, PhD, is a leading expert in behavioral pharmacology who has worked extensively with various multidisciplinary and multi-institutional teams focused on studies that use a wide range of methods from molecular to behavioral.

Dr. Wiley designs and supervises a program of in vivo research that complements existing strengths of the Center for Discovery and Analytical Sciences, including the synthesis and development of candidate medications and investigation of neural mechanisms underlying substance abuse. She also conducts independent National Institutes of Health grant-supported research in the area of cannabinoid pharmacology, an area in which she has an extensive record of peer-reviewed publications.

Before joining RTI in March 2010, Dr. Wiley was a professor in the Department of Pharmacology and Toxicology at VCU, where she still maintains an affiliate appointment. Additionally, she has been involved in governance of the International Cannabinoid Research Society for many years and served as the Society’s president at the 2013 meeting.


  • Postdoctoral Fellowship, Pharmacology, Virginia Commonwealth University
  • PhD, Biological Psychology, Virginia Commonwealth University
  • MS, Biological Psychology, Virginia Commonwealth University
  • BS, Psychology (minor: English), College of William and Mary

Latest Publications

Walentiny, D.M., Vann, R.E., & Wiley, J.L. (2015). Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice. Neuropharmacology, 93 :237-242.
Nguyen, T., German, N., Decker, A.M., Li, J.X., Wiley, J.L., Thomas, B.F., Kenakin, T.P., & Zhang, Y. (2015). Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators. Bioorganic and Medicinal Chemistry, 23 (9):2195-2203.
Wakley, A.A., Wiley, J.L., & Craft, R.M. (2015). Gonadal hormones do not alter the development of antinociceptive tolerance to delta-9-tetrahydrocannabinol in adult rats. Pharmacology, Biochemistry, and Behavior, Advance Online Publication .
Ignatowska-Jankowska, B.M., Wilkerson, J.L., Mustafa, M., Abdullah, R., Niphakis, M., Wiley, J.L., et al. (2015). Selective monoacylglycerol lipase inhibitors: Antinociceptive vs. cannabimimetic effects in mice. Journal of Pharmacology and Experimental Therapeutics, Advance Online Publication .
Wiley, J.L., Marusich, J.A., Thomas, B.F., & Jackson, K.J. (2015). Determination of behaviorally effective tobacco constituent doses in rats. Nicotine and Tobacco Research, 17 (3):368-371.
View all publications by Jenny L. Wiley (168)


  • Cannabinoid Pharmacology
  • Behavioral Pharmacology
  • Neuropharmacology
  • Animal Models of Substance Abuse