Download image: Brian Thomas
919-541-6552

Brian F. Thomas

Principal Scientist, Analytical Chemistry and Pharmaceutics

Brian F. Thomas, PhD, has more than 20 years of experience in analytical chemistry and mass spectrometry (MS). He is the principal investigator/co-principal investigator on two National Institute on Drug Abuse repository and purity specification contracts. He also holds an R01 grant with the National Institutes of Health. His principal duties include overseeing the development of chromatographic assays (gas chromatography [GC], high-performance liquid chromatography [HPLC], GC/MS, HPLC/MS) and spectrophotometric assays for the qualitative and quantitative analysis of bulk chemicals or chemicals in dosage formulations, biological fluids, tissues, or other complex matrices. Dr. Thomas was recently awarded RTI’s President’s Award for his scientific contributions to the institute.

Education

PhD, Pharmacology, Virginia Commonwealth University; BA, Biology, Kenyon College.

Latest Publications

Wiley, J.L., Marusich, J.A., Thomas, B.F., & Jackson, K.J. (2014). Determination of behaviorally effective tobacco constituent doses in rats. Nicotine and Tobacco Research, Advance Online Publication .
German, N., Decker, A.M., Gilmour, B.P., Gay, E.A., Wiley, J.L., Thomas, B.F., & Zhang, Y. (2014). Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure-Activity Relationship Studies on 1-(4-Chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). Journal of Medicinal Chemistry, 57 (18):7758-7769.
Thomas, B.F., Wiley, J.L., Pollard, G.T., & Grabenauer, M. (2014). Cannabinoid designer drugs: Effects and forensics. In Pertwee, R. (Ed.), Handbook of Cannabis (pp. 710-729). Oxford, UK: Oxford University Press.
Perrey, D.A., Gilmour, B.P., Thomas, B.F., & Zhang, Y. (2014). Toward the development of bivalent ligand probes of cannabinoid CB1 and orexin OX1 receptor heterodimers. Acs Medicinal Chemistry Letters, 5 (6):634-638.
Pozor, M.A., Zambrano, G., Roser, J., Hess, R., Runyon, S., Runcan, E., Thomas, B.F., et al. (2014). Acute and chronic effects of a contraceptive compound RTI-4587-073(l) on testicular histology and endocrine function in miniature horse stallions. Reproduction in Domestic Animals, 49 (3):392-402.
View all publications by Brian F. Thomas (89)

Expertise