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Brian F. Thomas

Director, Analytical Chemistry and Pharmaceutics

Brian F. Thomas, PhD, has more than 20 years of experience in analytical chemistry and mass spectrometry (MS). He is the principal investigator/co-principal investigator on two National Institute on Drug Abuse repository and purity specification contracts. He also holds an R01 grant with the National Institutes of Health. His principal duties include overseeing the development of chromatographic assays (gas chromatography [GC], high-performance liquid chromatography [HPLC], GC/MS, HPLC/MS) and spectrophotometric assays for the qualitative and quantitative analysis of bulk chemicals or chemicals in dosage formulations, biological fluids, tissues, or other complex matrices. Dr. Thomas was recently awarded RTI’s President’s Award for his scientific contributions to the institute.


PhD, Pharmacology, Virginia Commonwealth University; BA, Biology, Kenyon College.

Latest Publications

Pozor, M.A., Zambrano, G., Roser, J., Hess, R., Runyon, S., Runcan, E., Thomas, B.F., et al. (2014). Acute and chronic effects of a contraceptive compound RTI-4587-073(l) on testicular histology and endocrine function in miniature horse stallions. Reproduction in Domestic Animals, 49 (3):392-402.
Watterson, L.R., Kufahl, P.R., Nemirovsky, N.E., Sewalia, K., Grabenauer, M., Thomas, B.F., Marusich, J.A., et al. (2014). Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV). Addiction Biology, 19 (2):165-174.
Wiley, J.L., Marusich, J.A., Lefever, T.W., Grabenauer, M., Moore, K.N., & Thomas, B.F. (2013). Cannabinoids in disguise: Delta-Tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles. Neuropharmacology, 75 :145-154.
German, N.A., Decker, A.M., Gilmour, B.P., Thomas, B.F., & Zhang, Y.N. (2013). Truncated Orexin Peptides: Structure-Activity Relationship Studies. Acs Medicinal Chemistry Letters, 4 (12):1224-1227.
Perrey, D.A., German, N.A., Gilmour, B.P., Li, J.X., Harris, D.L., Thomas, B.F., & Zhang, Y. (2013). Substituted Tetrahydroisoquinolines as Selective Antagonists for the Orexin 1 Receptor. Journal of Medicinal Chemistry, 56 (17):6901-6916.
View all publications by Brian F. Thomas (85)