Barbara L. Kroner

Expertise

Viral and Chronic Disease Epidemiology
Multicenter Clinical Studies
Biospecimen Collection, Processing, and Transport

Biography

Barbara Kroner, PhD, is a senior epidemiologist in RTI’s Rockville, MD office, and has been with RTI since 1983. For the past 20 years, she has managed complex multicenter national and international epidemiologic studies of genetic and environmental risk factors related to viral and chronic disease, most notably outcomes related to HIV and HCV infection among persons with hemophilia and risk factors for aortic aneurysms and dissections in persons with Marfan and related syndromes. She also directs a study to determine the incidence and prevalence of epilepsy in Washington, DC. She has considerable knowledge regarding the practical techniques of biospecimen collection, processing, handling, and testing as components for epidemiologic studies. She was the chair of RTI’s Biospecimen Subcommittee under the Regulatory Affairs Working Group, which developed a new policy regarding infectious substances and diagnostics specimens. Dr. Kroner’s other research interests include Aicardi syndrome and the growth and development of children with disabilites.

Education

PhD, Epidemiology, University of Minnesota; MPH, Epidemiology, University of Minnesota; BS, Biochemistry, University of Wisconsin.

Selected Publications

Kroner, B.L., Preiss, L.R., Ardini, M.A., & Gaillard, W.D. (2008). New Incidence, prevalence, and survival of Aicardi Syndrome from 408 cases. Journal of Child Neurology, 23 (5):531-535.

Fried, M.W., Kroner, B.L., Preiss, L.R., Wilhelmsen, K., & Goedert, J.J. (2006). Hemophilic siblings with chronic hepatitis C: Familial aggregation of spontaneous and treatment-related viral clearance. Gastroenterology, 131 (3):757-764.

Theodore, D., Fried, M.W., Kleiner, D.E., Kroner, B.L., Goedert, J.J., Eyster, M.E., Faust, S.P., Sherman, K.E., Kessler, C.M., Francis, C., & Aledort, L.M. (2004). Liver biopsy in patients with inherited disorders of coagulation and chronic hepatitis C. Haemophilia, 10 (5):413-421.

Mariani, G., & Kroner, B. (2001 Nov). Immune tolerance in hemophilia with factor VIII inhibitors: predictors of success. Haematologica, 86 (11):1186-1193.

Astermark, J., Berntorp, E., White, G.C., & Kroner, B.L. (2001 May). The Malmo International Brother Study (MIBS): further support for genetic predisposition to inhibitor development in hemophilia patients. Haemophilia, 7 (3):267-272.

Kroner, B.L. (1999). Comparison of the International Immune Tolerance Registry and the North American Immune Tolerance Registry. Vox Sanguinis, 77:33-37.

Goedert, J.J., & Kroner, B.L. (1997). HIV-1 Infection in Hemophilia. In Forbes, C.D., L.M. Aledort, & R. Madhok (Ed.), Hemophilia (pp. 275-293). London: Chapman & Hall.

Kroner, B.L., Goedert, J.J., Blattner, W.A., Wilson, S.E., Carrington, M.N., & Mann, D.L. (1995 Mar). Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia Cohort and Hemophilia Growth and Development Studies. AIDS, 9 (3):275-280.

Kroner, B.L., Rosenberg, P.S., Aledort, L.M., Alvord, W.G., & Goedert, J.J. (1994 Mar). HIV-1 infection incidence among persons with hemophilia in the United States and western Europe, 1978-1990. Multicenter Hemophilia Cohort Study. Journal of Acquired Immune Deficiency Syndromes, 7 (3):279-286.

Bray, G.L., Kroner, B.L., Arkin, S., Aledort, L.W., Hilgartner, M.W., Eyster, M.E., Ragni, M.V., & Goedert, J.J. (1993 Apr). Loss of high-responder inhibitors in patients with severe hemophilia A and human immunodeficiency virus type 1 infection: a report from the Multi-Center Hemophilia Cohort Study. American Journal of Hematology, 42 (4):375-379.

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