RTI International Brochures

RTI is a leader in 3D integration technology, having demonstrated, in collaboration with commercial partner DRS, the first mixed-signal 3D bulk CMOS IC stack for infrared imaging applications. The RTI 3D integration technology platform includes through-silicon vias, high-density metal-metal and polymer bonding, and large-area multilevel metal routing. RTI is offering access to the technology platform through joint development projects, prototyping services and small volume production.

With more than 15 years of experience, RTI has an established track record in advanced gasification research. We have carried out various pilot-scale demonstrations of novel, sorbent-based syngas desulfurization technologies, as well as multi-contaminant control processes. We are also developing membrane materials/processes and catalytic processes for the conversion of coal to substitute natural gas, hydrogen, chemicals/fuels, and electricity. Our experience in coal gasification is also being leveraged into research programs devoted to biomass conversion and biofuels production.

RTI is home to one of the premier wafer bumping and flip chip packaging facilities in the U.S. Our experts in material and electronic technologies have more than 15 years of research, development, and implementation experience in all areas of bump interconnect technologies. From material characterization, to prototype and proof-ofconcept, to pilot-line and small-scale production, we tailor our capabilities to meet each client’s unique requirements.

To protect the nation’s most vulnerable and at-risk children, RTI International conducts a groundbreaking national study to help policy makers understand the characteristics and needs of children and families in the child welfare system. Sponsored by the Administration for Children and Families (ACF) within the U.S. Department of Health and Human Services, the National Survey of Child and Adolescent Well-Being (NSCAW) is the first nationally representative study of children and families involved in the U.S. child welfare system. RTI has worked with ACF since 1997 to conduct the study. Intended to answer fundamental questions about the outcomes for abused and neglected children, NSCAW collects data directly from children and caregivers. The data have increased understanding of policies and practices impacting child safety, permanence, and well-being, as well as child and caregiver services.

RTI studies a wide range of policy issues related to the health and long-term care of the elderly population and persons with disabilities. We focus on the availability, access, and payments for a full range of health, long-term care, and related social services for these populations.

A list of air filter and air cleaner testing services available through the Center for Aerosol Technology.

RTI offers four distinct hair reference materials, manufactured under strict quality control procedures, for forensic testing laboratories. These matrix-matched calibrators enhance the supportability of forensic data by allowing laboratories to include external reference materials with drugs of abuse at near cut-off/threshold concentrations in their analytical procedures.

RTI integrates ICT into international education projects to inform decision making, improve education policies and practices for education, and promote lifelong learning.

RTI works collaboratively with local and national stakeholders using information and communication technology (ICT) to improve health systems, strengthen information-based planning and ensure the efficient and effective delivery of health services.

ICT provides powerful tools to improve health care management and policy analysis. This brochure describes RTI's experience on various projects that apply ICT technologies to improve health.

Bios of RTI International statisticians who have been recognized by their peers as having made outstanding contributions to the field of statistics: Sally Morton, Paul Levy, Ty Hartwell, Ralph Folsom, Paul Biemer, and James Chromy

Through its Molecular Epidemiology, Genomics, Environment, and Health (MEGEH) partnership, RTI collaborates with academia and industry to conduct genomics studies and to fulfill its mission to improve the human condition. Our work may entail data collection from tens of thousands of people, the measurement of gene and protein expression, statistics, supercomputing, bioinformatics, biological assays, environmental assessments, or policy analysis.

Drawing on decades of experience in advanced gasification research and catalyst development, RTI is conducting R&D to help make biomass-to-liquid fuel processes technically and economically viable. Our scientists are developing process technologies to remove tar, ammonia, and sulfur from biomass gasification-derived syngas and are developing catalysts for converting syngas into transportation fuels. Other research focuses on co-gasification and also pyrolysis research.

RTI is qualified by the Division of Workplace Programs within the Substance Abuse and Mental Health Services Administration,as a supplier of
blind quality control (QC) urine samples for Federal workplace drug testing. we can custom-make reliable blind QC samples to meet your company’s needs.

RTI is actively developing technologies for capturing CO2 from fossil fuel–based combustion and gasification power plants. These include two novel processes for post-combustion capture: a sorbent-based technology and membrane-based technology. We are also developing a pre-combustion CO2 removal technology for the next generation of gasification-based power plants.

RTI has a fully functional on-site clinical pathology laboratory, where our highly trained clinical research scientists perform routine and specialized assays in support of government, commodity, and pharmaceutical clients.

RTI is a leader in the design and analysis of cluster-randomized and quasi-experimental studies and applies this extensive experience to plan effective program strategies, improve the quality of existing programs, and evaluate program effectiveness.

Tennessee State University, RTI International, and Jackson State Community College, with funding from the U.S. Department of Agriculture, are conducting research to evaluate consumer knowledge of recommended food safety practices and investigate effective training and information dissemination models to improve consumers' preparedness to respond to emergencies and foodborne bioterrorism.

RTI is a leader in the research, development, and prototyping of innovative materials, microstructures, and devices. Our labs are equipped with a wide variety of fabrication tools and processing capabilities. We support R&D for companies of all sizes, ranging from venture-funded start-ups to Fortune 100 companies.

As the data coordinating center for a multisite research study, RTI collaborates with the sponsor and with clinical investigators to design and implement clinical and behavioral epidemiological studies and clinical trials. Over the past three decades, RTI has served as the DCC for more than 25 multisite studies that include a strong portfolio in HIV/AIDS, maternal and child health, and other emerging public health challenges.

RTI is a world leader in data management for health research and evaluation, with significant experience designing and managing complex national, international, and multisite research studies and projects.

RTI has specialized in reproductive and developmental toxicity studies for more than 25 years. Led by Shelley Tyl, Ph.D., DABT, RTI has achieved a reputation for designing, executing, and reporting the findings of complex and comprehensive reproductive and developmental toxicology studies of the highest scientific caliber.

RTI’s eLearning initiatives are designed to • Increase access to education and training, especially in rural and remote areas • Enhance delivery of face-to-face training by incorporating ICT • Overcome geographical, social, health, or security barriers to regular communication and information exchange • Ensure delivery of flexible, locally tailored training to key stakeholders

RTI conducts election research in the United States and internationally through telephone, face-to-face, Web, and mail surveys. We have experience developing and evaluating training programs, and we offer expertise in electoral reform and civic education. Additionally, we apply GIS and spatial analysis techniques to improve the ballot casting process and study voting behavior across many geographic scales.

Overview of RTI's application of information and communication technology (ICT) to address democratic governance, transparency and accountability, citizen involvement, management, and information and service delivery.

For over 30 years, RTI has been conducting economic analyses to support the development and evaluation of environmental and natural resource management policies. We combine an indepth understanding of these policies with a broad range of analytical capabilities. These capabilities include the development and application of a large variety of economic modeling techniques designed to assess the benefits and costs of policy options. They also include the design of cost-effective policy instruments.

RTI has decades of experience supporting the steps involved in the FIFRA pesticide registration process. These capabilities include independent laboratory validation (ILV) of sampling and analysis methods, water monitoring, crop and soil analysis, and biologic sample analysis. Studies are performed in compliance with OECD guidelines, and work is conducted in compliance with Good Laboratory Practices (GLPs).

RTI has in-depth expertise in designing and carrying out successful surveys of commercial businesses, government agencies, health care organizations, and educational institutions and the employees, patients, faculty, staff, and students associated with them. Our experience includes the full range of activities—study design, sample design, instrument development and evaluation, pretests and pilot studies, mail surveys, telephone surveys, face-to-face field surveys, record abstraction, focus groups, health registries, and mixed-mode designs. Several of our recent establishment survey projects are highlighted here.

Since 1985, RTI has been analyzing and evaluating the effects of policies and regulations affecting the food, agricultural, and dietary supplement industries using a variety of methods and tools. We combine in-depth understanding of the food, agricultural, dietary supplement, and related industries with a broad range of capabilities.

Forensic science is a critical and rapidly growing field in the United States and abroad. RTI has capabilities in numerous areas if forensic science research, including workplace drug testing, performance testing, post mortem forensic toxicology, forensic operations and reporting systems, data collection and analysis, and drug testing in various biological matrices (i.e., urine, hair, and oral fluids).

RTI International is working with CDC to identify vulnerable populations and investigate the social, psychological, and environmental issues that may affect their resposnes to an influenza pandemic. RTI will then use these findings to assess CDC's materials for communicating information related to pandemic influenza.

RTI provides a full range of geographic information system (GIS) services to support public health, healthcare economics, and epidemiological research. Our experts model medical service markets, risk factors for disease, and other health outcomes to support informed decision making. We use a wide range of tools to create desktop and web-based GIS applications to meet specific client requirements.

RTI provides a full range of GIS services to support public safety and crime analysis. Working closely with criminologists and other social scientists, our GIS experts are able to fully understand the research requirements and, with that understanding, develop and implement the best geospatial solution.

Strengthening the pillars of a country’s health system—governance, finance, and operations—is essential to sustaining the impact of interventions and leading to better health outcomes for citizens. This brochure describes RTI's work in the area of health governance.

Under the TAMS contract, RTI will provide the CDC National Center for Chronic Disease Prevention and Health Promotion with “as-needed” services such as assistance conducting assessments, studies, research and demonstration projects, consultation and technical assistance, health education activities, and related support services.

RTI is an international leader in statistics, health, social policy, and survey research. With a local office in Atlanta, GA, RTI offers the Centers for Disease Control and Prevention a full range of public health, epidemiologic, and laboratory research support.

RTI is an international leader in statistics, health, social policy, and survey research. We are pleased to offer the Centers for Disease Control and Prevention a full range of public health, epidemiologic, and laboratory research support.

RTI designs and conducts multidisciplinary research that improves the physical, social, and emotional well-being of women, children, and families. We have research contracts and grants funded by the CDC, Administration for Children and Families, Assistant Secretary for Planning and Evaluation, Department of Education, Office of Population Affairs, National Institute of Child Health and Human Development, and Centers for Medicare & Medicaid Services.

RTI’s health services researchers evaluate health care organizations, focusing on internal interactions and the nature of internal/external relationships. We also examine workforce and resource allocations for the delivery of health services (medical and dental), as well as the characteristics of the persons served.

Health services researchers at RTI study policy issues in health care financing and reimbursement, including the design and evaluation of health care insurance, payment, and financing systems. Paying particular attention to the role of financial incentives in health care, we analyze costs, financial outcomes, quality, and efficiency.

Health care access, delivery, and organization critically influence public health and health care quality, outcomes, and cost. RTI International’s health services researchers evaluate health care organizations, focusing on internal interactions and the nature of internal/external relationships. RTI examines workforce and resource allocations for the delivery of health services, the characteristics of the persons served, and the interplay of these factors. We explore access of special populations to health services and the reduction in health disparities by race/ethnicity, disability or health status, and socioeconomic factors.

RTI measures and evaluates health care quality from numerous perspectives, including those of providers, payers, delivery systems, and patients/consumers. We develop models and indices to understand clinical interventions and organizational processes and their impact on patient outcomes, and we examine the effect of policy initiatives on the quality of health care services for populations and individuals.

Overview of how RTI’s research in health and risk communication helps clients convey crucial health information to diverse populations. RTI uses a variety of qualitative and quantitative methods. These include formative message development, focus groups, and case studies, materials design, cognitive and usability testing, process and outcome evaluations, expeimentally designed studies, and large-scale data collection and statistical analysis.

RTI International, through its research programs in the areas of health promotion and health communication, offers a range of research expertise to develop, support, and evaluate strategic health communications for HIV prevention and treatment.

RTI conducts research related to promoting effective communication, informed decision making, and healthy behaviors. To develop, test, disseminate, and evaluate informational messages directed at a target audience, we use a variety of qualitative and quantitative methods.

Government and private-sector clients around the world rely on RTI for independent, objective, and scientifically rigorous research in support of the care and treatment of people living with HIV. We recognize the importance of an integrated model of care and treatment, and we have the expertise to help clients develop and implement broad-based, multi-sectoral approaches to caring for HIV-infected adults and children.

Government and private-sector clients around the world rely on RTI for independent, objective, and scientifically rigorous research in support of the development of HIV drugs and therapeutics. We offer expertise in microbicides, immunization and vaccinology, and drug development.

Government and private-sector clients around the world rely on RTI for independent, objective, and scientifically rigorous research and technical services in support of HIV prevention programs.

RTI helps governments, NGOs, and communities implement and scale up programs, making the best use of recent increases in funding for the global fight against AIDS. Our technical support helps close gaps in capacity and overcome obstacles that impede the expansion of prevention, treatment, and care programs.

RTI's expertise in homeland security issues spans multiagency coordination and response, bioterrorism preparedness, health security, epidemiology, criminology and law enforcement, cyber security, economic analysis and modeling, immigration and population studies, data mining and predictive analytics, and survey research and geospatial modeling.

RTI International has the multifaceted knowledge and experience to help public health officials, policy makers, and other stakeholders in the field of immunization and vaccinology unravel the complicated network of factors that affect the development of vaccines and their introduction and use in real-world settings. Our capabilities span the basic sciences, policy and program evaluation, epidemiology, statistics, and surveys.

With more than 30 years of experience conducting DMPK studies, RTI is a leader in the metabolism and pharmacokinetics of pharmaceuticals, chemicals, and other xenobiotics in mammalian systems. We offer a variety of standard in vitro ADME-tox studies that can be tailored to client needs.

RTI is a leader in metabolism and pharmacokinetic studies of pharmaceuticals and other xenobiotics in mammalian systems. With more than 30 years of experience conducting drug metabolism and pharmacokinetics (DMPK) studies, our highly trained scientific staff offers innovative approaches to unique development issues.

This capability flyer describes the various projects RTI has undertaken in influenza-related research. These projects represent our capabilities in the areas of community preparedness, public health surveillance, health communications, mathematical modeling, economic analysis, and international health.

Before policy makers decide what steps to take to improve the nation’s drug use problem, they must know the reality. RTI International’s expertise in survey research provides that knowledge for informed decisions. The National Survey on Drug Use and Health (NSDUH) is the federal government’s primary source of national data on the use of alcohol, tobacco, and illicit substances. While providing annual national and state-level prevalence estimates, the survey also focuses on related topics, such as mental health, substance dependence and abuse, and the need for treatment. Sponsored by the Substance Abuse and Mental Health Services Administration (SAMHSA), NSDUH has been conducted successfully by RTI since 1988.

RTI is a leader in innovative health services research, and our health services research program is at the forefront of the President’s Health Information Technology initiative.

RTI International has demonstrated the ability to move promising lead compounds quickly and effectively through the formulation-optimization, preclinical and clinical studies required for regulatory approval of new therapeutics. To accomplish these high quality and timely outcomes, RTI brings the necessary combination of effective planning, management, technical and regulatory expertise to the drug development process.

RTI has a unique capacity for building cost-effective mathematical models and conducting virtual experiments for health outcomes. Our researchers use mathematical modeling and simulation techniques to evaluate disease dynamics, biological processes, environmental exposures, social interaction in disease behavior, and associated health outcomes. Application areas include HIV dynamics, substance use, cancer screening, sexually transmitted diseases, and planning for epidemic responses under different scenarios.

RTI generates and analyzes metabolomic data on behalf of government and commercial clients. By combining expertise in proteomics, bioinformatics, biochemistry, metabolite identification, data housing/repository, and field studies, we can design, conduct, and interpret results of complex metabolomic studies tailored to each client’s specific research needs.

RTI International provides technical support in the areas of microanalysis and microscopy to pharmaceutical and other commercial clients, as well as state and federal agencies. With a staff of experienced scientists and state-of-the-art laboratories and equipment, RTI conducts rigorous testing and analysis---enabling our clients to have complete confidence in the quality of our results.

Monitoring and evaluation (M&E) is a crucial part of strong program planning, implementation, and learning. Building strong and effective M&E requires technical skills, ingenuity, and judgment informed by project and contextual knowledge. RTI provides technical support in these areas, and incorporates our own Web-based tool to facilitate the management and use of M&E information.

This brochure describes the influenza research and evaluation services offered by RTI. Our approach to understanding the threat of an influenza pandemic is multidisciplinary, allowing us to offer a wide range of assistance to government and private-sector clients. Our experts apply social, statistical, and epidemiologic skills to examine numerous issues that affect influenza preparedness, response, and recovery.

As of fall 2007, RTI International is offering laboratories in the United States and Canada a proficiency testing (PT) program for alcohol and drugs in oral fluid. Forensic and research labs have long relied on RTI's Center for Forensic Sciences as a reliable source of PT samples, and many analytical facilities regard RTI as an important part of their quality assurance programs and certification efforts.

As of fall 2007, RTI International’s Center for Forensic Sciences offering European laboratories a proficiency testing (PT) program for alcohol and drugs in oral fluid. Forensic and research labs have long relied on RTI's Center for Forensic Sciences as a reliable source of PT samples, and many analytical facilities regard RTI as an important part of their quality assurance programmes and certification efforts.

RTI applies health economics and operations research to design, implement, analyze, and evaluate health care policy, with special emphasis on public health programs and interventions aimed at eliminating risk factors and improving health and quality of life. We perform cost-of-illness, cost effectiveness, cost-utility, cost-benefit, resource-allocation, and prevention-effectiveness analyses. Some of our public health economic studies are described here.

Rawabi, or “the hills” in English, is the first Palestinian planned community and it will take root 9 kilometers outside Ramallah. Between July and September 2008, RTI engaged with prominent Palestinian leaders of industry, education, and government; collected data; interviewed business stakeholders; mapped the assets of the region; and analyzed several industry sectors in which Palestine has a comparative advantage. At the end of this process, RTI produced a comprehensive economic growth strategy for Rawabi based on emerging realities in Palestine and the global economy.

RTI conducts research to ensure healthy development of children, from infancy through the transition to adulthood. We work within the child welfare, criminal justice, school, mental health, and community systems that touch at-risk children and their families. Our expertise encompasses the full cycle of research from etiologic studies to program evaluations and policy assessments. We bring state-of-the-art methods to our research, including both qualitative and quantitative techniques.

For decades, scientists at RTI have been studying the influence of drugs, chemicals, and stressors on specific genes, proteins, and metabolic processes. We develop biomarkers for preclinical and clinical applications, as well as for utilization in epidemiological studies to understand gene-environment interactions.

RTI has created an online analysis tool, RTI Analyst, that enables researchers, scientists, and policy makers to process data and view the results in a context-appropriate format. By presenting the analyses in a manner that is tailored to the research question, RTI Analyst provides maximum value to the user.

RTI has been active in Indonesia for the past 25 years, and in 1996, we opened a permanent office in Jakarta. Today, the RTI Indonesia office employs more than 300 local and international professionals with expertise in participatory planning and local governance, public finance, environmental management, health and education policy and programming, and private sector development.

RTI International partners with HHS to protect the health of all Americans. Our experience and expertise, available through the PSC IDIQ, span the broad fields of health, education and child care, employment, and environmental research.

RTI's South Africa office was established in September 2000 to expand our work in the region and to increase linkages with local partners and organizations. From its base in Pretoria, it is ideally placed to explore opportunities both in South Africa and more broadly in southern and eastern Africa.

RTI takes a cross-disciplinary approach to research and technical services, making it possible to study homeland and national security, health security, elections and government behavior, and human rights and civil society. We use epidemiological, social science, and survey research methods to provide risk assessments, program evaluations, pilot designs, full-scale studies, and theoretical research.

Small area estimation (SAE) is the process of using statistical models to link national or state survey outcome variables, such as disease indicators, to local area predictors, such as county demographic and socioeconomic (SES) variables, so that local area disease prevalence rates can be predicted. Social indicator variables such as age, race/ethnicity, gender, education, income, family structure, and employment status are commonly used to define high-risk subpopulations for targeting health promotion and disease prevention. Under the direction of internationally renowned statistician, Dr. Ralph E. Folsom, an ASA fellow, RTI has been implementing SAE methodology on numerous projects for several years.

RTI is dedicated to assisting clients develop the appropriate animal models for efficacy and safety testing of their compounds. We design specialty studies and develop unique animal models to ensure the most rapid route to IND submission.

RTI has a strong history in the economic analysis of the benefits and costs of treatment programs and health interventions targeted at substance abuse problems. Our Substance Abuse Services Cost Analysis Program (SASCAP) reliably estimates costs of substance abuse treatment services without excessive burden on treatment programs.

RTI International supports a wide range of HIV/AIDS epidemiological and clinical activities both in the United States and globally. Our diverse capabilities allow us to conduct research and provide technical assistance in HIV/AIDS prevention, care, and treatment.

Government agencies and industry rely on RTI to solve real-world, trace element speciation problems. Using state-of-the-art instrumentation, our experts develop and apply unique qualitative and quantitative methods to determine trace elements in environmental, biological, geological, and clinical samples.

RTI performs trace metals analyses and methods development research in support of many types of environmental research. We work for federal, state, and local agencies, as well as commercial companies to monitor the health of the food chain and support compliance with environmental regulations.

RTI performs trace metals analyses and methods development research in support of many types of health research. We work for federal, state, and local agencies, as well as universities and commercial companies. Our clients rely on RTI’s national reputation for excellence to meet their need for timely and accurate results.

RTI has developed Trinity Sight, a methodology for preparing and analyzing data on violent crime. Trinity Sight provides integrated analysis of the time, space, and nature of suspicious incidents. We have used this methodology to evaluate over a million 911 call records, identifying several hundred incidents indicative of pre-attack surveillance activity.

RTI International has conducted projects in water and sanitation planning, utility management, local government service delivery and financing, environmental health, and water resource management. We have built a reputation for excellence in program design, implementation, and evaluation with the U.S. Agency for International Development (USAID), the Asian Development Bank (ADB), The World Bank, United Nations agencies, and private sector clients.